PDB: 1544 件ウェブページステータス検索Chemie searchBIRD

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4DHZ	The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub 分子名称: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... 著者 Wiener, R, Zhang, X, Wang, T, Wolberger, C. 登録日 2012-01-30 公開日 2012-02-22 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
6Y0G	Structure of human ribosome in classical-PRE state 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. 登録日 2020-02-07 公開日 2020-04-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
6Z6L	Cryo-EM structure of human CCDC124 bound to 80S ribosomes 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. 登録日 2020-05-28 公開日 2020-07-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
3A33	UbcH5b~Ubiquitin Conjugate 分子名称: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2 著者 Sakata, E, Satoh, T, Yamamoto, S, Yamaguchi, Y, Yagi-Utsumi, M, Kurimoto, E, Wakatsuki, S, Kato, K. 登録日 2009-06-08 公開日 2009-11-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of UbcH5b~Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2~Ub Conjugates Structure, 18, 2010
4ZUX	SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome 分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Morgan, M, Wolberger, C. 登録日 2015-05-17 公開日 2016-02-24 最終更新日 2016-03-09 実験手法 X-RAY DIFFRACTION (3.82 Å) 主引用文献 Structural basis for histone H2B deubiquitination by the SAGA DUB module. Science, 351, 2016
5A5B	Structure of the 26S proteasome-Ubp6 complex 分子名称: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... 著者 Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F. 登録日 2015-06-17 公開日 2015-07-22 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (9.5 Å) 主引用文献 Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 112, 2015
5AIT	A complex of of RNF4-RING domain, UbeV2, Ubc13-Ub (isopeptide crosslink) 分子名称: E3 UBIQUITIN-PROTEIN LIGASE RNF4, POLYUBIQUITIN-C, UBIQUITIN-CONJUGATING ENZYME E2 N, ... 著者 Branigan, E, Naismith, J.H. 登録日 2015-02-17 公開日 2015-07-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural Basis for the Ring Catalyzed Synthesis of K63 Linked Ubiquitin Chains Nat.Struct.Mol.Biol., 22, 2015
5AIU	A complex of RNF4-RING domain, Ubc13-Ub (isopeptide crosslink) 分子名称: 1,2-ETHANEDIOL, E3 UBIQUITIN-PROTEIN LIGASE RNF4, POLYUBIQUITIN-C, ... 著者 Branigan, E, Naismith, J.H. 登録日 2015-02-17 公開日 2015-07-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural Basis for the Ring Catalyzed Synthesis of K63 Linked Ubiquitin Chains Nat.Struct.Mol.Biol., 22, 2015
5EYA	TRIM25 RING domain in complex with Ubc13-Ub conjugate 分子名称: Polyubiquitin-B, Tripartite motif-containing 25 variant, Ubiquitin-conjugating enzyme E2 N, ... 著者 Pornillos, O, Sanchez, J.G. 登録日 2015-11-24 公開日 2016-08-17 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway. Cell Rep, 16, 2016
3OJ4	Crystal structure of the A20 ZnF4, ubiquitin and UbcH5A complex 分子名称: Tumor necrosis factor alpha-induced protein 3, Ubiquitin, Ubiquitin-conjugating enzyme E2 D1, ... 著者 Bosanac, I, Hymowitz, S.G. 登録日 2010-08-20 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling Mol.Cell, 40, 2010
3PTF	X-ray structure of the non-covalent complex between UbcH5A and Ubiquitin 分子名称: Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D1 著者 Bosanac, I, Hymowitz, S.G. 登録日 2010-12-02 公開日 2011-05-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Modulation of K11-Linkage Formation by Variable Loop Residues within UbcH5A. J.Mol.Biol., 408, 2011
5FER	Complex of TRIM25 RING with UbcH5-Ub 分子名称: E3 ubiquitin/ISG15 ligase TRIM25, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D1, ... 著者 Rittinger, K, Koliopoulos, M.G, Esposito, D. 登録日 2015-12-17 公開日 2016-05-18 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity. Embo J., 35, 2016
5HPT	System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: WWP1, Ubv P2.3 and UBCH7 分子名称: NEDD4-like E3 ubiquitin-protein ligase WWP1, Ubiquitin variant P2.3, Ubiquitin-conjugating enzyme E2 L3 著者 Wu, K.-P, Schulman, B.A. 登録日 2016-01-20 公開日 2016-03-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
5FLX	Mammalian 40S HCV-IRES complex 分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... 著者 Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T. 登録日 2015-10-28 公開日 2015-12-23 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA. Embo J., 34, 2015
5GAK	Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A 分子名称: 25S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 5.8S rRNA, ... 著者 Schmidt, C, Becker, T. 登録日 2015-12-09 公開日 2016-02-24 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.88 Å) 主引用文献 Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome. Nucleic Acids Res., 44, 2016
5GJQ	Structure of the human 26S proteasome bound to USP14-UbAl 分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... 著者 Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G. 登録日 2016-07-01 公開日 2016-08-17 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 An atomic structure of the human 26S proteasome. Nat. Struct. Mol. Biol., 23, 2016
5H7S	Structural basis of the flanking zinc-finger motifs crucial for the E3 ligase activity of the LNX1 RING domain 分子名称: E3 ubiquitin-protein ligase LNX, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-like 1, ... 著者 Nayak, D, Sivaraman, J. 登録日 2016-11-21 公開日 2017-11-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.49 Å) 主引用文献 Structure of LNX1:Ubc13~Ubiquitin Complex Reveals the Role of Additional Motifs for the E3 Ligase Activity of LNX1. J. Mol. Biol., 430, 2018
5IFR	Structure of the stable UBE2D3-UbDha conjugate 分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D3 著者 Pruneda, J.N, Mulder, M.P.C, Witting, K, Ovaa, H, Komander, D. 登録日 2016-02-26 公開日 2016-05-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes. Nat.Chem.Biol., 12, 2016
2EKE	Structure of a SUMO-binding-motif mimic bound to Smt3p-Ubc9p: conservation of a noncovalent Ubiquitin-like protein-E2 complex as a platform for selective interactions within a SUMO pathway 分子名称: SUMO-conjugating enzyme UBC9, Ubiquitin-like protein SMT3 著者 Duda, D.M, Schulman, B.A. 登録日 2007-03-23 公開日 2007-05-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of a SUMO-binding-motif Mimic Bound to Smt3p-Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein-E2 Complex as a Platform for Selective Interactions within a SUMO Pathway J.Mol.Biol., 369, 2007
2FUH	Solution Structure of the UbcH5c/Ub Non-covalent Complex 分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 D3 著者 Brzovic, P.S, Lissounov, A, Hoyt, D.W, Klevit, R.E. 登録日 2006-01-26 公開日 2006-03-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination. Mol.Cell, 21, 2006
2GMI	Mms2/Ubc13~Ubiquitin 分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 13, Ubiquitin-conjugating enzyme variant MMS2 著者 Wolberger, C, Eddins, M.J, Carlile, C.M, Gomez, K.G, Pickart, C.M. 登録日 2006-04-06 公開日 2006-09-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation. Nat.Struct.Mol.Biol., 13, 2006
3UGB	UbcH5c~Ubiquitin Conjugate 分子名称: GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3 著者 Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S. 登録日 2011-11-02 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates. Biochemistry, 51, 2012
5Z57	Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ... 著者 Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. 登録日 2018-01-17 公開日 2018-09-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
8XSX	Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2024-01-10 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8XSZ	Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2024-01-10 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024

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