5H7S
Structural basis of the flanking zinc-finger motifs crucial for the E3 ligase activity of the LNX1 RING domain
Summary for 5H7S
Entry DOI | 10.2210/pdb5h7s/pdb |
Related | 5H7R |
Descriptor | Ubiquitin-like 1, E3 ubiquitin-protein ligase LNX, Ubiquitin-conjugating enzyme E2 N, ... (4 entities in total) |
Functional Keywords | ring, ubiquitin, e3 ligase, zinc finger motif, protein binding-ligase-transferase complex, protein binding/ligase/transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Ubiquitin: Cytoplasm : P0CG47 Cytoplasm : Q8TBB1 Nucleus : P61088 |
Total number of polymer chains | 6 |
Total formula weight | 81180.22 |
Authors | Nayak, D.,Sivaraman, J. (deposition date: 2016-11-21, release date: 2017-11-29, Last modification date: 2023-11-08) |
Primary citation | Nayak, D.,Sivaraman, J. Structure of LNX1:Ubc13~Ubiquitin Complex Reveals the Role of Additional Motifs for the E3 Ligase Activity of LNX1. J. Mol. Biol., 430:1173-1188, 2018 Cited by PubMed: 29496391DOI: 10.1016/j.jmb.2018.02.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.49 Å) |
Structure validation
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