5H7S

Structural basis of the flanking zinc-finger motifs crucial for the E3 ligase activity of the LNX1 RING domain

Summary for 5H7S

• Entry DOI: 10.2210/pdb5h7s/pdb
• Related: 5H7R
• Descriptor: Ubiquitin-like 1, E3 ubiquitin-protein ligase LNX, Ubiquitin-conjugating enzyme E2 N, ... (4 entities in total)
• Functional Keywords: ring, ubiquitin, e3 ligase, zinc finger motif, protein binding-ligase-transferase complex, protein binding/ligase/transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Ubiquitin: Cytoplasm : P0CG47; Cytoplasm : Q8TBB1; Nucleus : P61088
• Total number of polymer chains: 6
• Total formula weight: 81180.22

Authors

Nayak, D.,Sivaraman, J. (deposition date: 2016-11-21, release date: 2017-11-29, Last modification date: 2023-11-08)

• Primary citation: Nayak, D.,Sivaraman, J.; Structure of LNX1:Ubc13~Ubiquitin Complex Reveals the Role of Additional Motifs for the E3 Ligase Activity of LNX1.; J. Mol. Biol., 430:1173-1188, 2018; PubMed: 29496391; DOI: 10.1016/j.jmb.2018.02.016

Experimental method

X-RAY DIFFRACTION (3.49 Å)