PDB: 327 件ウェブページステータス検索Chemie searchBIRD

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1L9Z	Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution 分子名称: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... 著者 Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A. 登録日 2002-03-27 公開日 2002-05-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (6.5 Å) 主引用文献 Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex. Science, 296, 2002
8DY7	Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors 分子名称: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Campbell, E.A. 登録日 2022-08-03 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
8DY9	Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors 分子名称: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Campbell, E.A. 登録日 2022-08-03 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
4G7O	Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA 分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.993 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012
1L9U	THERMUS AQUATICUS RNA POLYMERASE HOLOENZYME AT 4 A RESOLUTION 分子名称: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... 著者 Murakami, K.S, Masuda, S, Darst, S.A. 登録日 2002-03-26 公開日 2002-05-22 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution. Science, 296, 2002
4G7Z	Crystal structure of Thermus thermophilus transcription initiation complex containing 5-BrU at template-strand position +1 分子名称: 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*(BRU)P*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.815 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012
1L0O	Crystal Structure of the Bacillus stearothermophilus Anti-Sigma Factor SpoIIAB with the Sporulation Sigma Factor SigmaF 分子名称: ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, MAGNESIUM ION, ... 著者 Campbell, E.A, Masuda, S, Sun, J.L, Muzzin, O, Olson, C.A, Wang, S, Darst, S.A. 登録日 2002-02-12 公開日 2002-04-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF. Cell(Cambridge,Mass.), 108, 2002
4G7H	Crystal structure of Thermus thermophilus transcription initiation complex 分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012
2A6E	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-02 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
2A6H	Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Temiakov, D, Zenkin, N, Vassylyeva, M.N, Perederina, A, Tahirov, T.H, Savkina, M, Zorov, S, Nikiforov, V, Igarashi, N, Matsugaki, N, Wakatsuki, S, Severinov, K, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-02 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis of transcription inhibition by antibiotic streptolydigin. Mol.Cell, 19, 2005
2A69	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-02 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
2A68	Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-01 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
1ZYR	Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ... 著者 Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. 登録日 2005-06-10 公開日 2005-09-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation. Cell(Cambridge,Mass.), 122, 2005
2BE5	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with inhibitor tagetitoxin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Vassylyev, D.G, Svetlov, V, Vassylyeva, M.N, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Artsimovitch, I, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-10-22 公開日 2005-11-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for transcription inhibition by tagetitoxin Nat.Struct.Mol.Biol., 12, 2005
2CW0	Crystal structure of Thermus thermophilus RNA polymerase holoenzyme at 3.3 angstroms resolution 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark Jr, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. 登録日 2005-06-15 公開日 2005-09-20 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation Cell(Cambridge,Mass.), 122, 2005
8FTD	Structure of Escherichia coli CedA in complex with transcription initiation complex 分子名称: CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, M, Vassyliev, N, Nudler, E. 登録日 2023-01-11 公開日 2024-01-10 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 General transcription factor from Escherichia coli with a distinct mechanism of action. Nat.Struct.Mol.Biol., 31, 2024
8GZH	Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc 分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 You, L.L, Shen, L.Q, Zhang, Y. 登録日 2022-09-27 公開日 2023-04-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc Proc.Natl.Acad.Sci.USA, 2023
8GZG	Cryo-EM structure of Synechocystis sp. PCC 6803 RPitc 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Shen, L.Q, You, L.L, Zhang, Y. 登録日 2022-09-27 公開日 2023-04-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc Proc.Natl.Acad.Sci.USA, 2023
8HKC	Cryo-EM structure of E. coli RNAP sigma32 complex 分子名称: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Wu, S, Ma, L.X. 登録日 2022-11-25 公開日 2023-05-31 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.49 Å) 主引用文献 Structural Insight into the Mechanism of sigma 32-Mediated Transcription Initiation of Bacterial RNA Polymerase. Biomolecules, 13, 2023
8H3V	Cryo-EM structure of the full transcription activation complex NtcA-NtcB-TAC 分子名称: DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z. 登録日 2022-10-09 公開日 2023-10-04 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31, 2024
8H40	Cryo-EM structure of the transcription activation complex NtcA-TAC 分子名称: DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z. 登録日 2022-10-09 公開日 2023-10-04 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31, 2024
7LQ4	Rr (RsiG)2-(c-di-GMP)2-WhiG complex 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), RsiG, WhiG 著者 Schumacher, M.A, Brennan, R.G. 登録日 2021-02-12 公開日 2021-07-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Evolution of a sigma-(c-di-GMP)-anti-sigma switch. Proc.Natl.Acad.Sci.USA, 118, 2021
4MEY	Crystal structure of Escherichia coli RNA polymerase holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. 登録日 2013-08-27 公開日 2014-05-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.948 Å) 主引用文献 Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
4NQW	Structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor SigK in complex with the cytosolic domain of its cognate anti-sigma factor RskA 分子名称: Anti-sigma-K factor RskA, CADMIUM ION, ECF RNA polymerase sigma factor SigK 著者 Shukla, J.K, Gopal, B. 登録日 2013-11-25 公開日 2014-01-22 最終更新日 2014-04-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for the redox sensitivity of the Mycobacterium tuberculosis SigK-RskA sigma-anti-sigma complex Acta Crystallogr.,Sect.D, 70, 2014
4OIQ	Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 and rifampicin 分子名称: (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ... 著者 Zhang, Y, Ebright, R.H, Arnold, E. 登録日 2014-01-20 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.624 Å) 主引用文献 GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014

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