8H3V

Cryo-EM structure of the full transcription activation complex NtcA-NtcB-TAC

Summary for 8H3V

Entry DOI	10.2210/pdb8h3v/pdb
EMDB information	34475
Descriptor	DNA (125-MER), NtcA, DNA-directed RNA polymerase subunit beta, ... (10 entities in total)
Functional Keywords	transcription activation complex, coordinated regulation, transcription
Biological source	Anabaena More
Total number of polymer chains	15
Total formula weight	718729.42
Authors	Han, S.J.,Jiang, Y.L.,You, L.L.,Shen, L.Q.,Wu, X.X.,Yang, F.,Kong, W.W.,Chen, Z.P.,Zhang, Y.,Zhou, C.Z. (deposition date: 2022-10-09, release date: 2023-10-04, Last modification date: 2024-02-28)
Primary citation	Han, S.J.,Jiang, Y.L.,You, L.L.,Shen, L.Q.,Wu, X.,Yang, F.,Cui, N.,Kong, W.W.,Sun, H.,Zhou, K.,Meng, H.C.,Chen, Z.P.,Chen, Y.,Zhang, Y.,Zhou, C.Z. DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31:293-299, 2024 Cited by PubMed: 38177666 DOI: 10.1038/s41594-023-01149-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.5 Å)

Structure validation