8H40

Cryo-EM structure of the transcription activation complex NtcA-TAC

Summary for 8H40

Entry DOI	10.2210/pdb8h40/pdb
EMDB information	34475 34476
Descriptor	DNA (125-MER), DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (9 entities in total)
Functional Keywords	transcription activation complex, transcription
Biological source	Anabaena More
Total number of polymer chains	11
Total formula weight	578963.97
Authors	Han, S.J.,Jiang, Y.L.,You, L.L.,Shen, L.Q.,Wu, X.X.,Yang, F.,Kong, W.W.,Chen, Z.P.,Zhang, Y.,Zhou, C.Z. (deposition date: 2022-10-09, release date: 2023-10-04, Last modification date: 2024-02-28)
Primary citation	Han, S.J.,Jiang, Y.L.,You, L.L.,Shen, L.Q.,Wu, X.,Yang, F.,Cui, N.,Kong, W.W.,Sun, H.,Zhou, K.,Meng, H.C.,Chen, Z.P.,Chen, Y.,Zhang, Y.,Zhou, C.Z. DNA looping mediates cooperative transcription activation. Nat.Struct.Mol.Biol., 31:293-299, 2024 Cited by PubMed: 38177666 DOI: 10.1038/s41594-023-01149-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation