4NQW
Structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor SigK in complex with the cytosolic domain of its cognate anti-sigma factor RskA
Replaces: 3VDOSummary for 4NQW
Entry DOI | 10.2210/pdb4nqw/pdb |
Descriptor | ECF RNA polymerase sigma factor SigK, Anti-sigma-K factor RskA, CADMIUM ION, ... (4 entities in total) |
Functional Keywords | sigma factor, transcription initiation, dna binding, promoter dna binding and transcription initiation, anti-sigma factor, dna binding protein-protein binding complex, dna binding protein/protein binding |
Biological source | Mycobacterium tuberculosis More |
Cellular location | Cell membrane; Single-pass membrane protein (Potential): O53729 |
Total number of polymer chains | 2 |
Total formula weight | 32651.35 |
Authors | Shukla, J.K.,Gopal, B. (deposition date: 2013-11-25, release date: 2014-01-22, Last modification date: 2014-04-16) |
Primary citation | Shukla, J.,Gupta, R.,Thakur, K.G.,Gokhale, R.,Gopal, B. Structural basis for the redox sensitivity of the Mycobacterium tuberculosis SigK-RskA sigma-anti-sigma complex Acta Crystallogr.,Sect.D, 70:1026-1036, 2014 Cited by PubMed: 24699647DOI: 10.1107/S1399004714000121 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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