PDB: 160 件ウェブページステータス検索Chemie searchBIRD

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4PKZ	Crystal structure of P1M mutant of Macrophage Migration Inhibitory Factor 分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION 著者 Pantouris, G, Lolis, E. 登録日 2014-05-15 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
4PLU	Crystal structure of Macrophage Migration Inhibitory Factor in complex with benzaldehyde 分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION, ... 著者 Pantouris, G, Lolis, E. 登録日 2014-05-19 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
4TRF	Crystal structure of Macrophage Migration Inhibitory Factor in complex with N-(pyridin-3-ylmethyl)thioformamide 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2014-06-16 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
4TRU	Crystal structure of Q24A Q25A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2014-06-17 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
4WRB	Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-190) 分子名称: 4-{4-[6-(2-methoxyethoxy)quinolin-2-yl]-1H-1,2,3-triazol-1-yl}phenol, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L. 登録日 2014-10-23 公開日 2015-03-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. J.Am.Chem.Soc., 137, 2015
4WR8	Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-180) 分子名称: 4-[4-(quinolin-2-yl)-1H-1,2,3-triazol-1-yl]phenol, Macrophage migration inhibitory factor, SODIUM ION, ... 著者 Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L. 登録日 2014-10-23 公開日 2015-03-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. J.Am.Chem.Soc., 137, 2015
4XX7	Crystal structure of M2A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2015-01-29 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
4XX8	Crystal structure of Pro1 deletion mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION 著者 Pantouris, G, Lolis, E. 登録日 2015-01-30 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
4Z15	MIF in complex with 3-(2-furylmethyl)-2-thioxo-1,3-thiazolan-4-one 分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION 著者 Cho, T.Y. 登録日 2015-03-26 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors. J. Cell. Mol. Med., 21, 2017
4Z1U	MIF in complex with 1-(4-methylphenyl)-3-phenylprop-2-yn-1-one 分子名称: GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION 著者 Cho, T.Y. 登録日 2015-03-27 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors. J. Cell. Mol. Med., 21, 2017
4Z1T	MIF in complex with 4-[(4-oxo-2-thioxo-1,3-thiazolan-3-yl)methyl]benzonitrile 分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION 著者 Cho, T.Y. 登録日 2015-03-27 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors. J. Cell. Mol. Med., 21, 2017
5BSC	Crystal structure of K66A mutant of human macrophage migration inhibitory factor 分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor 著者 Pantouris, G, Lolis, E. 登録日 2015-06-01 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
5BS9	Crystal structure of N109A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2015-06-01 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
5BSI	Crystal structure of Y36A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION 著者 Pantouris, G, Lolis, E. 登録日 2015-06-02 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
5BSJ	Crystal structure of S63A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2015-06-02 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of S63A mutant of human macrophage migration inhibitory factor To Be Published
5EIZ	Crystal structure of Y99A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2015-10-30 公開日 2015-11-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74. Angew. Chem. Int. Ed. Engl., 2018
5HVT	Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Potent Inhibitor (NVS-2) 分子名称: 7-hydroxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1,3-benzoxazin-2-one, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Robertson, M.J, Jorgensen, W.L. 登録日 2016-01-28 公開日 2016-06-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors. J.Am.Chem.Soc., 138, 2016
5HVV	Crystal structure of Pro1 deletion and M2A double mutant of Macrophage Migration Inhibitory Factor 分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION 著者 Pantouris, G, Lolis, E. 登録日 2016-01-28 公開日 2016-02-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of P1 deletion and M2A double mutant of Macrophage Migration Inhibitory Factor To Be Published
5HVS	Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Biaryltriazole Inhibitor (3i-305) 分子名称: 3-({2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]quinolin-5-yl}oxy)benzoic acid, GLYCEROL, Macrophage migration inhibitory factor, ... 著者 Robertson, M.J, Jorgensen, W.L. 登録日 2016-01-28 公開日 2016-06-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors. J.Am.Chem.Soc., 138, 2016
5J7P	Macrophage Migration Inhibitory Factor bound to Covalent Inhibitor RDR03785 分子名称: 6-{[4-(trifluoromethyl)phenyl]methyl}-2H-1,3-benzodioxol-5-ol, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Robertson, M.J, Jorgensen, W.L. 登録日 2016-04-06 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Irregularities in enzyme assays: The case of macrophage migration inhibitory factor. Bioorg.Med.Chem.Lett., 26, 2016
5J7Q	Macrophage Migration Inhibitory Factor bound to Inhibitor K664 Derivative 分子名称: 4-(imidazo[1,2-a]pyridin-2-yl)benzene-1,2-diol, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Robertson, M.J, Jorgensen, W.L. 登録日 2016-04-06 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Irregularities in enzyme assays: The case of macrophage migration inhibitory factor. Bioorg.Med.Chem.Lett., 26, 2016
5B4O	Crystal structure of Macrophage Migration Inhibitory Factor in complex with BTZO-14 分子名称: 1,2-ETHANEDIOL, 2-pyridin-3-yl-1,3-benzothiazin-4-one, Macrophage migration inhibitory factor, ... 著者 Oki, H, Igaki, S, Moriya, Y, Hayano, Y, Habuka, N. 登録日 2016-04-07 公開日 2016-04-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression Chem. Biol., 17, 2010
5UMJ	Crystal structure of H62A mutant of human macrophage migration inhibitory factor 分子名称: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION 著者 Pantouris, G, Lolis, E. 登録日 2017-01-27 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
5UMK	Crystal structure of H62Y mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2017-01-27 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
5UZY	Crystal structure of N97A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2017-02-27 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74. Angew. Chem. Int. Ed. Engl., 57, 2018

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