5UZY
Crystal structure of N97A mutant of human macrophage migration inhibitory factor
Summary for 5UZY
Entry DOI | 10.2210/pdb5uzy/pdb |
Descriptor | Macrophage migration inhibitory factor, SULFATE ION, ISOPROPYL ALCOHOL, ... (5 entities in total) |
Functional Keywords | isomerase, trimeric, mutation |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 37592.72 |
Authors | Pantouris, G.,Lolis, E. (deposition date: 2017-02-27, release date: 2018-02-28, Last modification date: 2023-10-04) |
Primary citation | Pantouris, G.,Ho, J.,Shah, D.,Syed, M.A.,Leng, L.,Bhandari, V.,Bucala, R.,Batista, V.S.,Loria, J.P.,Lolis, E.J. Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74. Angew. Chem. Int. Ed. Engl., 57:7116-7119, 2018 Cited by PubMed: 29669180DOI: 10.1002/anie.201803191 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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