5UZY

Crystal structure of N97A mutant of human macrophage migration inhibitory factor

Summary for 5UZY

• Entry DOI: 10.2210/pdb5uzy/pdb
• Descriptor: Macrophage migration inhibitory factor, SULFATE ION, ISOPROPYL ALCOHOL, ... (5 entities in total)
• Functional Keywords: isomerase, trimeric, mutation
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 37592.72

Authors

Pantouris, G.,Lolis, E. (deposition date: 2017-02-27, release date: 2018-02-28, Last modification date: 2023-10-04)

• Primary citation: Pantouris, G.,Ho, J.,Shah, D.,Syed, M.A.,Leng, L.,Bhandari, V.,Bucala, R.,Batista, V.S.,Loria, J.P.,Lolis, E.J.; Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.; Angew. Chem. Int. Ed. Engl., 57:7116-7119, 2018; PubMed: 29669180; DOI: 10.1002/anie.201803191

Experimental method

X-RAY DIFFRACTION (1.71 Å)