5EIZ

Crystal structure of Y99A mutant of human macrophage migration inhibitory factor

Summary for 5EIZ

Entry DOI	10.2210/pdb5eiz/pdb
Descriptor	Macrophage migration inhibitory factor, GLYCEROL, SULFATE ION, ... (5 entities in total)
Functional Keywords	isomerase, surface, mutation
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	37473.54
Authors	Pantouris, G.,Lolis, E. (deposition date: 2015-10-30, release date: 2015-11-11, Last modification date: 2023-09-27)
Primary citation	Pantouris, G.,Ho, J.,Shah, D.,Syed, M.A.,Leng, L.,Bhandari, V.,Bucala, R.,Batista, V.S.,Loria, J.P.,Lolis, E.J. Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74. Angew. Chem. Int. Ed. Engl., 2018 Cited by PubMed: 29669180 DOI: 10.1002/anie.201803191 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.96 Å)

Structure validation