4XX8

Crystal structure of Pro1 deletion mutant of human macrophage migration inhibitory factor

Summary for 4XX8

Entry DOI	10.2210/pdb4xx8/pdb
Related	4GRN 4GRO 4P01 4P0H 4PKZ 4PLU 4TRF 4TRU 4XX7 5BS9 5BSC 5BSI
Descriptor	Macrophage migration inhibitory factor, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	isomerase, surface, mutation
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P14174
Total number of polymer chains	3
Total formula weight	37530.42
Authors	Pantouris, G.,Lolis, E. (deposition date: 2015-01-30, release date: 2015-09-30, Last modification date: 2023-09-27)
Primary citation	Pantouris, G.,Syed, M.A.,Fan, C.,Rajasekaran, D.,Cho, T.Y.,Rosenberg, E.M.,Bucala, R.,Bhandari, V.,Lolis, E.J. An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22:1197-1205, 2015 Cited by PubMed: 26364929 DOI: 10.1016/j.chembiol.2015.08.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.77 Å)

Structure validation