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8UNS
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BU of 8uns by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class H)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNR
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BU of 8unr by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class G)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNQ
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BU of 8unq by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class F)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNP
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BU of 8unp by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class E)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNO
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BU of 8uno by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class D)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNN
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BU of 8unn by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class C)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNM
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BU of 8unm by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class B)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNL
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BU of 8unl by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class A)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UHB
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BU of 8uhb by Molmil
Cryo-EM Structure of the Ro5256390-bound hTA1-Gs heterotrimer signaling complex
分子名称: (2R,4S)-4-[(2S)-2-phenylbutyl]-1,3-oxazolidin-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zilberg, G, Warren, A.L, Parpounas, A.K, Wacker, D.
登録日2023-10-08
公開日2024-01-10
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Molecular basis of human trace amine-associated receptor 1 activation.
Nat Commun, 15, 2024
8UH3
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BU of 8uh3 by Molmil
Serotonin 1E receptor (5-HT1eR)-Gi1 Complex bound with Setiptiline
分子名称: 5-hydroxytryptamine receptor 1E, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Wacker, D, Parpounas, A.K, Warren, A.L, Zilberg, G.
登録日2023-10-06
公開日2024-05-01
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R.
Sci Adv, 10, 2024
8UGY
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BU of 8ugy by Molmil
Serotonin 1E receptor (5-HT1eR)-Gi1 Complex bound with Mianserin
分子名称: 5-hydroxytryptamine receptor 1E, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zilberg, G, Warren, A.L, Wacker, D.
登録日2023-10-06
公開日2024-05-01
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R.
Sci Adv, 10, 2024
8U8F
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BU of 8u8f by Molmil
GPR3 Orphan G-coupled Protein Receptor in complex with Dominant Negative Gs.
分子名称: G-protein coupled receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Russell, I.C, Belousoff, M.J, Sexton, P.
登録日2023-09-17
公開日2024-03-06
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3.
Biochemistry, 63, 2024
8U84
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BU of 8u84 by Molmil
KCTD5/Cullin3/Gbeta1gamma2 Complex: State D From Composite RELION Multi-body Refinement Map
分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U83
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BU of 8u83 by Molmil
KCTD5/Cullin3/Gbeta1gamma2 Complex: State C From Composite RELION Multi-body Refinement Map
分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.975 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U82
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BU of 8u82 by Molmil
KCTD5/Cullin3/Gbeta1gamma2 Complex: State B From Composite RELION Multi-body Refinement Map
分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U81
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BU of 8u81 by Molmil
KCTD5/Cullin3/Gbeta1gamma2 Complex: State A From Composite RELION Multi-body Refinement Map
分子名称: BTB/POZ domain-containing protein KCTD5, Cullin-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U7Z
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BU of 8u7z by Molmil
KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinment of KCTD5(CTD)/Gbeta1gamma2
分子名称: BTB/POZ domain-containing protein KCTD5, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
著者Kuntz, D.A, Nguyen, D.M, Narayanan, N, Prive, G.G.
登録日2023-09-15
公開日2023-10-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure and dynamics of a pentameric KCTD5/CUL3/G beta gamma E3 ubiquitin ligase complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U4Q
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BU of 8u4q by Molmil
Structure of REGN7663 Fab-bound CXCR4/Gi complex
分子名称: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4P
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BU of 8u4p by Molmil
Structure of AMD3100-bound CXCR4/Gi complex
分子名称: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4O
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BU of 8u4o by Molmil
Structure of CXCL12-bound CXCR4/Gi complex
分子名称: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4N
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BU of 8u4n by Molmil
Structure of Apo CXCR4/Gi complex
分子名称: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Saotome, K, McGoldrick, L.L, Franklin, M.C.
登録日2023-09-11
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U26
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BU of 8u26 by Molmil
Gaussian Mixture Models based single particle refinement - GPCR (Substance P bound to active human neurokinin 1 receptor in complex with miniGs399 from EMPIAR-10786)
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Chen, M, Pintilie, G.
登録日2023-09-05
公開日2023-11-15
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models.
Nat.Methods, 21, 2024
8U1U
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BU of 8u1u by Molmil
Structure of a class A GPCR/agonist complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Sun, D, Johnson, M, Masureel, M.
登録日2023-09-02
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
8THL
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BU of 8thl by Molmil
Cryo-EM structure of epinephrine-bound alpha-1A-adrenergic receptor in complex with heterotrimeric Gq-protein
分子名称: Endolysin,Alpha-1A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Su, M, Huang, X.Y.
登録日2023-07-17
公開日2023-08-16
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of agonist specificity of alpha 1A -adrenergic receptor.
Nat Commun, 14, 2023
8THK
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BU of 8thk by Molmil
Cryo-EM structure of A61603-bound alpha-1A-adrenergic receptor in complex with heterotrimeric Gq-protein
分子名称: Endolysin,Alpha-1A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Su, M, Huang, X.Y.
登録日2023-07-17
公開日2023-08-16
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of agonist specificity of alpha 1A -adrenergic receptor.
Nat Commun, 14, 2023

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件を2024-06-12に公開中

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