8U7Z

KCTD5/Cullin3/Gbeta1gamma2 Complex: Local Refinment of KCTD5(CTD)/Gbeta1gamma2

This is a non-PDB format compatible entry.

Summary for 8U7Z

• Entry DOI: 10.2210/pdb8u7z/pdb
• EMDB information: 41994
• Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, BTB/POZ domain-containing protein KCTD5 (3 entities in total)
• Functional Keywords: cullin family protein, proteasome-mediated ubiquitin-dependent protein catabolic process, complex, ubiquitin-dependent protein catabolic process, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 15
• Total formula weight: 356937.85

Authors

Kuntz, D.A.,Nguyen, D.M.,Narayanan, N.,Prive, G.G. (deposition date: 2023-09-15, release date: 2023-10-11, Last modification date: 2024-04-24)

• Primary citation: Nguyen, D.M.,Rath, D.H.,Devost, D.,Petrin, D.,Rizk, R.,Ji, A.X.,Narayanan, N.,Yong, D.,Zhai, A.,Kuntz, D.A.,Mian, M.U.Q.,Pomroy, N.C.,Keszei, A.F.E.,Benlekbir, S.,Mazhab-Jafari, M.T.,Rubinstein, J.L.,Hebert, T.E.,Prive, G.G.; Structure and dynamics of a pentameric KCTD5/Cullin3/G beta gamma E3 ubiquitin ligase complex; Proc.Natl.Acad.Sci.USA, 2024; DOI: 10.1073/pnas.2315018121

Experimental method

ELECTRON MICROSCOPY (2.97 Å)