8U1U

Structure of a class A GPCR/agonist complex

Summary for 8U1U

• Entry DOI: 10.2210/pdb8u1u/pdb
• EMDB information: 41829
• Descriptor: C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
• Functional Keywords: gpcr, agonist, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 202143.62

Authors

Sun, D.,Johnson, M.,Masureel, M. (deposition date: 2023-09-02, release date: 2023-12-20)

• Primary citation: Sun, D.,Sun, Y.,Janezic, E.,Zhou, T.,Johnson, M.,Azumaya, C.,Noreng, S.,Chiu, C.,Seki, A.,Arenzana, T.L.,Nicoludis, J.M.,Shi, Y.,Wang, B.,Ho, H.,Joshi, P.,Tam, C.,Payandeh, J.,Comps-Agrar, L.,Wang, J.,Rutz, S.,Koerber, J.T.,Masureel, M.; Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.; Nat Commun, 14:7940-7940, 2023; PubMed: 38040762; DOI: 10.1038/s41467-023-43601-8

Experimental method

ELECTRON MICROSCOPY (3.1 Å)