8U4P

Structure of AMD3100-bound CXCR4/Gi complex

Summary for 8U4P

• Entry DOI: 10.2210/pdb8u4p/pdb
• EMDB information: 41888 41889 41890 41891 41892 41893 41894
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpcr, chemokine receptor, plerixafor, amd3100, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 159939.56

Authors

Saotome, K.,McGoldrick, L.L.,Franklin, M.C. (deposition date: 2023-09-11, release date: 2024-03-13)

• Primary citation: Saotome, K.,McGoldrick, L.L.,Ho, J.,Ramlall, T.,Shah, S.,Moore, M.J.,Kim, J.H.,Leidich, R.,Olson, W.C.,Franklin, M.C.; Structural insights into CXCR4 modulation and oligomerization; Biorxiv, 2024; DOI: 10.1101/2024.02.09.579708

Experimental method

ELECTRON MICROSCOPY (3.15 Å)