8U26

Gaussian Mixture Models based single particle refinement - GPCR (Substance P bound to active human neurokinin 1 receptor in complex with miniGs399 from EMPIAR-10786)

Summary for 8U26

Entry DOI	10.2210/pdb8u26/pdb
EMDB information	24570 41840
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywords	gpcr, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	141549.56
Authors	Chen, M.,Pintilie, G. (deposition date: 2023-09-05, release date: 2023-11-15, Last modification date: 2024-01-24)
Primary citation	Chen, M.,Schmid, M.F.,Chiu, W. Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models. Nat.Methods, 21:37-40, 2024 Cited by PubMed: 37973972 DOI: 10.1038/s41592-023-02082-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation