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4Y3K
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BU of 4y3k by Molmil
Structure of Vaspin mutant E379S
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Serpin A12
著者Pippel, J, Strater, N, Ulbricht, D, Schultz, S, Meier, R, Heiker, J.T.
登録日2015-02-10
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A unique serpin P1' glutamate and a conserved beta-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin).
Biochem.J., 470, 2015
3PZF
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BU of 3pzf by Molmil
1.75A resolution structure of Serpin-2 from Anopheles gambiae
分子名称: Serpin 2
著者Lovell, S, Battaile, K.P, An, C, Michel, K.
登録日2010-12-14
公開日2011-02-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of native Anopheles gambiae serpin-2, a negative regulator of melanization in mosquitoes.
Proteins, 79, 2011
3Q03
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BU of 3q03 by Molmil
Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation.
分子名称: CHLORIDE ION, Plasminogen activator inhibitor 1, ZINC ION
著者Jensen, J.K, Morth, J.P.
登録日2010-12-15
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6401 Å)
主引用文献Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability.
J.Biol.Chem., 286, 2011
3UT3
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BU of 3ut3 by Molmil
A novel PAI-I inhibitor and its structural mechanism
分子名称: 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione, Plasminogen activator inhibitor 1
著者Lin, Z.H, Hong, Z.B, Shi, X.L, Hu, L.H, Andreasen, P.A, Huang, M.D.
登録日2011-11-25
公開日2013-02-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献A novel PAI-I inhibitor and its structural mechanism
To be Published
4ZK0
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BU of 4zk0 by Molmil
Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. High pH structure
分子名称: Serpin B4, ZINC ION
著者Helland, R, Lysvand, H, Slupphaug, G, Iversen, O.J.
登録日2015-04-29
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates.
Biochem Biophys Rep, 2, 2015
4ZK3
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Psoriasis pathogenesis - Pso p27 constitute a compact structure forming large aggregates. Low pH structure
分子名称: Serpin B3
著者Helland, R, Lysvand, H, Slupphaug, G, Iversen, O.J.
登録日2015-04-29
公開日2015-07-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates.
Biochem Biophys Rep, 2, 2015
4Y40
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BU of 4y40 by Molmil
Structure of Vaspin mutant D305C V383C
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Serpin A12
著者Pippel, J, Strater, N, Ulbricht, D, Schultz, S, Meier, R, Heiker, J.T.
登録日2015-02-10
公開日2015-08-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A unique serpin P1' glutamate and a conserved beta-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin).
Biochem.J., 470, 2015
3Q02
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BU of 3q02 by Molmil
Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation.
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Plasminogen activator inhibitor 1, ...
著者Jensen, J.K, Morth, J.P.
登録日2010-12-15
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability.
J.Biol.Chem., 286, 2011
3ZHA
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BU of 3zha by Molmil
Molecular basis for the action of the collagen-specific chaperone Hsp47 SERPINH1 and its structure-specific client recognition.
分子名称: COLLAGEN MODEL PEPTIDE 18-T8R11, HSP47, SUCCINIC ACID
著者Widmer, C, Gebauer, J.M, Baumann, U.
登録日2012-12-20
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition.
Proc.Natl.Acad.Sci.USA, 109, 2012
1UHG
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BU of 1uhg by Molmil
Crystal Structure of S-Ovalbumin At 1.9 Angstrom Resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ovalbumin, ...
著者Yamasaki, M, Takahashi, N, Hirose, M.
登録日2003-07-03
公開日2003-07-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of S-ovalbumin as a Non-loop-inserted Thermostabilized Serpin Form
J.Biol.Chem., 278, 2003
4YIA
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BU of 4yia by Molmil
Structural mechanism of hormone release in thyroxine binding globulin
分子名称: CALCIUM ION, CHLORIDE ION, INDOMETHACIN, ...
著者Zheng, Y.
登録日2015-03-01
公開日2016-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural mechanism of hormone release in thyroxine Binding globulin
To Be Published
3T1P
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BU of 3t1p by Molmil
Crystal structure of an alpha-1-antitrypsin trimer
分子名称: Alpha-1-antitrypsin
著者Huntington, J.A, Yamasaki, M.
登録日2011-07-22
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Molecular basis of alpha 1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer.
EMBO Rep., 12, 2011
1T1F
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BU of 1t1f by Molmil
Crystal Structure of Native Antithrombin in its Monomeric Form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, GLYCEROL, ...
著者Johnson, D.J.D, Huntington, J.A.
登録日2004-04-16
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation
J.Biol.Chem., 281, 2006
3STO
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BU of 3sto by Molmil
Serpin from the trematode Schistosoma Haematobium
分子名称: Serine protease inhibitor
著者Granzin, J, Weiergraeber, O.H, Lee, X, Blanton, R.E.
登録日2011-07-11
公開日2012-05-30
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain.
Acta Crystallogr.,Sect.D, 68, 2012
4AFX
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BU of 4afx by Molmil
Crystal structure of the reactive loop cleaved ZPI in I2 space group
分子名称: CALCIUM ION, PHOSPHATE ION, PROTEIN Z DEPENDENT PROTEASE INHIBITOR, ...
著者Zhou, A, Yan, Y, Wei, Z.
登録日2012-01-23
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z.
Blood, 120, 2012
4AJU
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BU of 4aju by Molmil
Crystal structure of the reactive loop cleaved ZPI in P41 space group
分子名称: 1,2-ETHANEDIOL, PROTEIN Z-DEPENDENT PROTEASE INHIBITOR, SULFATE ION
著者Zhou, A, Yan, Y, Wei, Z.
登録日2012-02-19
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z.
Blood, 120, 2012
4AJT
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BU of 4ajt by Molmil
The crystal structure of mouse protein-Z dependent protease inhibitor(mZPI)
分子名称: PROTEIN Z-DEPENDENT PROTEASE INHIBITOR
著者Yan, Y, Zhou, A.
登録日2012-02-19
公開日2012-12-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z.
Blood, 120, 2012
4AQH
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BU of 4aqh by Molmil
Plasminogen activator inhibitor type-1 in complex with the inhibitor AZ3976
分子名称: PLASMINOGEN ACTIVATOR INHIBITOR 1, TERT-BUTYL 3-[(4-OXO-3H-PYRIDO[2,3-D]PYRIMIDIN-2-YL)AMINO]AZETIDINE-1-CARBOXYLATE
著者Fjellstrom, O, Deinum, J, Sjogren, T, Johansson, C, Geschwindner, S, Nerme, V, Legnehed, A, McPheat, J, Olsson, K, Bodin, C, Gustafsson, D.
登録日2012-04-17
公開日2012-11-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 that Accelerates the Transition Into the Latent Conformation
J.Biol.Chem., 288, 2013
1SNG
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BU of 1sng by Molmil
Structure of a Thermophilic Serpin in the Native State
分子名称: COG4826: Serine protease inhibitor, SULFATE ION
著者Fulton, K.F, Buckle, A.M, Cabrita, L.D, Irving, J.A, Butcher, R.E, Smith, I, Reeve, S, Lesk, A.M, Bottomley, S.P, Rossjohn, J, Whisstock, J.C.
登録日2004-03-10
公開日2004-12-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition.
J.Biol.Chem., 280, 2005
3R4L
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BU of 3r4l by Molmil
Human very long half life Plasminogen Activator Inhibitor type-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasminogen activator inhibitor 1, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yang, J, Zheng, H, Han, Q, Skrzypczak-Jankun, E, Jankun, J.
登録日2011-03-17
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Remarkable extension of PAI-1 half-life surprisingly brings no changes to its structure.
Int.J.Mol.Med., 29, 2012
2ZNH
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BU of 2znh by Molmil
Crystal Structure of a Domain-Swapped Serpin Dimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ...
著者Yamasaki, M, Huntington, J.A.
登録日2008-04-25
公開日2008-10-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization
Nature, 455, 2008
6F4V
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BU of 6f4v by Molmil
Crystal structure of cleaved Kallistatin complexed with heparin at 1.8 Angstrom resolution
分子名称: 1,2-ETHANEDIOL, 3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, CHLORIDE ION, ...
著者Zhou, A, Wei, Z.
登録日2017-11-30
公開日2018-12-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of human Kallistatin
To Be Published
6F02
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Crystal structure of human glycosylated kallistatin at 3.0 Angstrom resolution
分子名称: Kallistatin, SULFATE ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhou, A, Ma, L.
登録日2017-11-17
公開日2018-12-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human Kallistatin
To Be Published
6F4U
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BU of 6f4u by Molmil
Crystal structure of reactive loop cleaved kallistatin at 1.9 angstrom resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者Zhou, A, Wei, Z, Lin, F.
登録日2017-11-30
公開日2018-12-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human Kallistatin
To Be Published
2XN3
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Crystal structure of thyroxine-binding globulin complexed with mefenamic acid
分子名称: 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID, THYROXINE-BINDING GLOBULIN
著者Qi, X, Yan, Y, Wei, Z, Zhou, A.
登録日2010-07-30
公開日2011-02-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins.
J.Biol.Chem., 286, 2011

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