5OM7
Crystal structure of Alpha1-antichymotrypsin variant DBS-II: a drug-binding serpin for doxorubicin
Summary for 5OM7
| Entry DOI | 10.2210/pdb5om7/pdb |
| Descriptor | Alpha-1-antichymotrypsin, DOXORUBICIN, ... (4 entities in total) |
| Functional Keywords | serpin, alpha1-antichymotrypsin, doxorubicin-binding protein, protein design, transport protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 47164.50 |
| Authors | Schmidt, K.,Kern, A.,Muller, Y.A. (deposition date: 2017-07-28, release date: 2018-05-23, Last modification date: 2018-06-06) |
| Primary citation | Schmidt, K.,Gardill, B.R.,Kern, A.,Kirchweger, P.,Borsch, M.,Muller, Y.A. Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115:5744-5749, 2018 Cited by PubMed: 29760101DOI: 10.1073/pnas.1716666115 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.727 Å) |
Structure validation
Download full validation report
