4Y40
Structure of Vaspin mutant D305C V383C
Summary for 4Y40
Entry DOI | 10.2210/pdb4y40/pdb |
Related | 4IF8 4Y3K |
Descriptor | Serpin A12, 1,2-ETHANEDIOL, SULFATE ION, ... (4 entities in total) |
Functional Keywords | serpin, adipokine, exosite, signaling protein, hydrolase inhibitor, hydrloase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: Q8IW75 |
Total number of polymer chains | 2 |
Total formula weight | 95702.40 |
Authors | Pippel, J.,Strater, N.,Ulbricht, D.,Schultz, S.,Meier, R.,Heiker, J.T. (deposition date: 2015-02-10, release date: 2015-08-12, Last modification date: 2024-01-10) |
Primary citation | Ulbricht, D.,Pippel, J.,Schultz, S.,Meier, R.,Strater, N.,Heiker, J.T. A unique serpin P1' glutamate and a conserved beta-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin). Biochem.J., 470:357-367, 2015 Cited by PubMed: 26199422DOI: 10.1042/BJ20150643 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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