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1NQ9

Crystal Structure of Antithrombin in the Pentasaccharide-Bound Intermediate State

Summary for 1NQ9
Entry DOI10.2210/pdb1nq9/pdb
Related1E03 1E04 1E05 1OYH
Related PRD IDPRD_900031
DescriptorAntithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ... (5 entities in total)
Functional Keywordsthrombin; inhibition; heparin analogue; serine protease inhibitor, blood clotting
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P01008
Total number of polymer chains2
Total formula weight103240.48
Authors
Huntington, J.A.,Johnson, D.J.D. (deposition date: 2003-01-21, release date: 2003-09-30, Last modification date: 2024-03-13)
Primary citationJohnson, D.J.D.,Huntington, J.A.
Crystal Structure of Antithrombin in a Heparin-Bound Intermediate State
Biochemistry, 42:8712-8719, 2003
Cited by
PubMed: 12873131
DOI: 10.1021/bi034524y
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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