PDB: 100 件ウェブページステータス検索Chemie searchBIRD

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7LKY	Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641 分子名称: DIMETHYL SULFOXIDE, Isoform 1 of PHD finger protein 1, Peptidomimetic inhibitor UNC6641, ... 著者 Liu, J, Kutateladze, T.G. 登録日 2021-02-03 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1). J.Med.Chem., 64, 2021
7E29	Crystal Structure of Saccharomyces cerevisiae Ioc4 PWWP domain fused with MBP 分子名称: Maltose/maltodextrin-binding periplasmic protein,ISWI one complex protein 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Li, J, Smolle, M, Liang, H, Liu, Y. 登録日 2021-02-05 公開日 2022-02-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.303 Å) 主引用文献 H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function. Nucleic Acids Res., 50, 2022
7EA8	Human SETD2 bound to a nucleosome containing oncohistone mutations 分子名称: 601-DNA, Histone H2A type 1-D, Histone H2B type 2-E, ... 著者 Jing, H, Liu, Y. 登録日 2021-03-06 公開日 2021-07-14 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations. Cell Discov, 7, 2021
7EA5	Yeast Set2 bound to a nucleosome containing oncohistone mutations 分子名称: 601-DNA, Histone H2A, Histone H2B, ... 著者 Jing, H, Liu, Y. 登録日 2021-03-06 公開日 2021-07-14 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations. Cell Discov, 7, 2021
7YI4	Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in close state 分子名称: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... 著者 Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. 登録日 2022-07-14 公開日 2023-06-14 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.96 Å) 主引用文献 Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
7YI2	Cryo-EM structure of Rpd3S in loose-state Rpd3S-NCP complex 分子名称: Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... 著者 Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. 登録日 2022-07-14 公開日 2023-06-14 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
7YI3	Cryo-EM structure of Rpd3S in close-state Rpd3S-NCP complex 分子名称: Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... 著者 Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. 登録日 2022-07-14 公開日 2023-06-14 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
7YI1	Cryo-EM structure of Eaf3 CHD bound to H3K36me3 nucleosome 分子名称: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... 著者 Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. 登録日 2022-07-14 公開日 2023-06-14 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
7YI0	Cryo-EM structure of Rpd3S complex 分子名称: Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... 著者 Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. 登録日 2022-07-14 公開日 2023-06-14 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
7YI5	Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in loose state 分子名称: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... 著者 Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. 登録日 2022-07-14 公開日 2023-06-14 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.96 Å) 主引用文献 Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
8EIK	Cryo-EM structure of human DNMT3B homo-hexamer 分子名称: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Lu, J.W, Song, J.K. 登録日 2022-09-15 公開日 2023-09-20 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. Nucleic Acids Res., 51, 2023
8EII	Cryo-EM structure of human DNMT3B homo-tetramer (form II) 分子名称: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Lu, J.W, Song, J.K. 登録日 2022-09-15 公開日 2023-09-20 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. Nucleic Acids Res., 51, 2023
8EIH	Cryo-EM structure of human DNMT3B homo-tetramer (form I) 分子名称: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Lu, J.W, Song, J.K. 登録日 2022-09-15 公開日 2023-09-20 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. Nucleic Acids Res., 51, 2023
8EIJ	Cryo-EM structure of human DNMT3B homo-trimer 分子名称: DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Lu, J.W, Song, J.K. 登録日 2022-09-15 公開日 2023-09-20 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. Nucleic Acids Res., 51, 2023
8HXX	Cryo-EM structure of the histone deacetylase complex Rpd3S 分子名称: Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ... 著者 Cui, H, Wang, H. 登録日 2023-01-05 公開日 2023-09-27 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
8HXY	Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome 分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ... 著者 Cui, H, Wang, H. 登録日 2023-01-05 公開日 2023-09-27 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
8HY0	Composite cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome 分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ... 著者 Cui, H, Wang, H. 登録日 2023-01-05 公開日 2023-09-27 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
8HXZ	Cryo-EM structure of Eaf3 CHD in complex with nucleosome 分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ... 著者 Cui, H, Wang, H. 登録日 2023-01-05 公開日 2023-09-27 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
8CBQ	structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome 分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ... 著者 Koutna, E, Kouba, T, Novacek, J, Veverka, V. 登録日 2023-01-25 公開日 2023-09-06 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
8CBN	structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome 分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ... 著者 Koutna, E, Kouba, T, Novacek, J, Veverka, V. 登録日 2023-01-25 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
8IFG	Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe 分子名称: Chromatin modification-related protein eaf3, Cph1, Cph2, ... 著者 Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D. 登録日 2023-02-17 公開日 2024-01-03 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Class I histone deacetylase complex: Structure and functional correlates. Proc Natl Acad Sci U S A, 120, 2023
8JHO	Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with di-nucleosome 分子名称: Chromatin modification-related protein EAF3, Di-nucleosome template foward, Di-nucleosome template reverse, ... 著者 Wang, H. 登録日 2023-05-25 公開日 2023-09-27 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
8PC5	H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex 分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ... 著者 Koutna, E, Kouba, T, Veverka, V. 登録日 2023-06-09 公開日 2023-08-16 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
8PC6	H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex - pose 2 分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ... 著者 Koutna, E, Kouba, T, Veverka, V. 登録日 2023-06-09 公開日 2023-08-16 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
8Q5P	Structure of the lysine methyltransferase SETD2 in complex with a peptide derived from human tyrosine kinase ACK1 分子名称: Activated CDC42 kinase 1, Histone-lysine N-methyltransferase SETD2, S-ADENOSYLMETHIONINE, ... 著者 Mechaly, A, Le Coadou, L, Dupret, J.M, Haouz, A, Rodrigues Lima, F. 登録日 2023-08-09 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.814 Å) 主引用文献 Structural and enzymatic evidence for the methylation of the ACK1 tyrosine kinase by the histone lysine methyltransferase SETD2. Biochem.Biophys.Res.Commun., 695, 2024

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