8HXY

Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome

Summary for 8HXY

• Entry DOI: 10.2210/pdb8hxy/pdb
• EMDB information: 35082
• Descriptor: Histone H3, Transcriptional regulatory protein RCO1, ZINC ION, ... (11 entities in total)
• Functional Keywords: histone deacetylase complex, rpd3s-nucleosome complex, histone deacetylation, gene regulation
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 15
• Total formula weight: 753121.82

Authors

Cui, H.,Wang, H. (deposition date: 2023-01-05, release date: 2023-09-27, Last modification date: 2023-12-27)

• Primary citation: Li, W.,Cui, H.,Lu, Z.,Wang, H.; Structure of histone deacetylase complex Rpd3S bound to nucleosome.; Nat.Struct.Mol.Biol., 30:1893-1901, 2023; PubMed: 37798513; DOI: 10.1038/s41594-023-01121-5

Experimental method

ELECTRON MICROSCOPY (3.1 Å)