8EIK

Cryo-EM structure of human DNMT3B homo-hexamer

Summary for 8EIK

Entry DOI	10.2210/pdb8eik/pdb
EMDB information	28156 28157 28158 28159
Descriptor	DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION (3 entities in total)
Functional Keywords	dna methyltransferase, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	6
Total formula weight	443862.28
Authors	Lu, J.W.,Song, J.K. (deposition date: 2022-09-15, release date: 2023-09-20, Last modification date: 2023-12-20)
Primary citation	Lu, J.,Fang, J.,Zhu, H.,Liang, K.L.,Khudaverdyan, N.,Song, J. Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. Nucleic Acids Res., 51:12476-12491, 2023 Cited by PubMed: 37941146 DOI: 10.1093/nar/gkad972 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.19 Å)

Structure validation