7WD8
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7KPN
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7WBO
| Crystal structure of Sarcoplasmic Calcium-Binding Protein from Scylla paramamosain | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... | 著者 | Chen, Y, Jin, T, Liu, G. | 登録日 | 2021-12-17 | 公開日 | 2022-12-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure Analysis of Sarcoplasmic-Calcium-Binding Protein: An Allergen in Scylla paramamosain. J.Agric.Food Chem., 71, 2023
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7WD1
| Crystal structure of R14 bound to SARS-CoV-2 RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, R14, Spike protein S1, ... | 著者 | Wang, Q.H, Gao, G.F, Qi, J.X, Su, C, Liu, H.H, Wu, L.L. | 登録日 | 2021-12-20 | 公開日 | 2022-12-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice. Cell Rep Med, 4, 2023
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7KFA
| PCSK9 in complex with PCSK9i a 13mer cyclic peptide LDLR disruptor | 分子名称: | 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, CALCIUM ION, Proprotein convertase subtilisin/kexin type 9, ... | 著者 | Chopra, R, Xu, M, Spraggon, G. | 登録日 | 2020-10-13 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Identification of a PCSK9-LDLR disruptor peptide with in vivo function. Cell Chem Biol, 29, 2022
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7KEV
| PCSK9 in complex with a cyclic peptide LDLR disruptor | 分子名称: | CALCIUM ION, Proprotein convertase subtilisin/kexin type 9, Proprotein convertase subtilisin/kexin type 9 Propeptide, ... | 著者 | Spraggon, G, Chopra, R. | 登録日 | 2020-10-12 | 公開日 | 2021-11-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Identification of a PCSK9-LDLR disruptor peptide with in vivo function. Cell Chem Biol, 29, 2022
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7UVK
| G. haemolysans IgA1 protease | 分子名称: | IgA1 Protease | 著者 | Eisenmesser, E.Z, Zheng, H. | 登録日 | 2022-05-02 | 公開日 | 2022-11-23 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases. Commun Biol, 5, 2022
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7UVL
| IgA1 Protease with IgA1 substrate | 分子名称: | Immunoglobulin alpha-1 heavy chain, Immunoglobulin alpha-1 heavy constant, Immunoglobulin alpha-1 light chain, ... | 著者 | Eisenmesser, Z.E, Zheng, H. | 登録日 | 2022-05-02 | 公開日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | 主引用文献 | A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases. Commun Biol, 5, 2022
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7JZL
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7WG6
| Neutral Omicron Spike Trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Cui, Z, Wang, X. | 登録日 | 2021-12-28 | 公開日 | 2022-05-18 | 最終更新日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron. Cell, 185, 2022
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7UJA
| Cryo-EM structure of Human respiratory syncytial virus F variant (construct pXCS847A) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AM14 Fab heavy chain, AM14 Fab light chain, ... | 著者 | Lees, J.A, Ammirati, M, Han, S. | 登録日 | 2022-03-30 | 公開日 | 2023-04-19 | 最終更新日 | 2023-05-10 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine. Sci Transl Med, 15, 2023
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7UJ3
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7JZM
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7JZN
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7XBF
| The complex structure of RshSTT182/200 RBD-insert2 bound to human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, RshSTT182/200 coronavirus receptor binding domain insert2, ... | 著者 | Hu, Y, Liu, K.F, Han, P, Qi, J.X. | 登録日 | 2022-03-21 | 公開日 | 2023-01-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.51 Å) | 主引用文献 | Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs. Embo J., 42, 2023
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7XBG
| The crystal structure of RshSTT182/200 RBD-insert2-T346R-Y496G mutant in complex with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Hu, Y, Liu, K.F, Han, P, Qi, J.X. | 登録日 | 2022-03-21 | 公開日 | 2023-01-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | 主引用文献 | Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs. Embo J., 42, 2023
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7XBH
| The complex structure of RshSTT182/200 RBD bound to human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, RshSTT182/200 coronavirus receptor binding domain, ... | 著者 | Hu, Y, Liu, K.F, Han, P, Qi, J.X. | 登録日 | 2022-03-21 | 公開日 | 2023-01-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs. Embo J., 42, 2023
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7X4I
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7WD2
| Crystal structure of S43 bound to SARS-CoV-2 RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, Q.H, Gao, G.F, Qi, J.X, Su, C, Liu, H.H, Wu, L.L. | 登録日 | 2021-12-20 | 公開日 | 2022-12-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice. Cell Rep Med, 4, 2023
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7LIR
| Structure of the invertebrate ALK GRD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor homolog scd-2, ... | 著者 | Stayrook, S, Li, T, Klein, D.E. | 登録日 | 2021-01-27 | 公開日 | 2021-11-24 | 最終更新日 | 2021-12-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for ligand reception by anaplastic lymphoma kinase. Nature, 600, 2021
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7LS0
| Structure of the Human ALK GRD bound to AUG | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor fused with ALK and LTK ligand 2, CITRIC ACID | 著者 | Stayrook, S, Li, T, Klein, D.E. | 登録日 | 2021-02-17 | 公開日 | 2021-11-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural basis for ligand reception by anaplastic lymphoma kinase. Nature, 600, 2021
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7LRZ
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7K0C
| Structure of Secretory IgM Core | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, Immunoglobulin heavy constant mu, ... | 著者 | Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L. | 登録日 | 2020-09-04 | 公開日 | 2021-01-20 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the human secretory immunoglobulin M core. Structure, 29, 2021
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7JZU
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7W1S
| Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-007 | 分子名称: | Nanobody Nb-007, Spike protein S1 | 著者 | Yang, J, Lin, S, Sun, H.L, Lu, G.W. | 登録日 | 2021-11-20 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | A Potent Neutralizing Nanobody Targeting the Spike Receptor-Binding Domain of SARS-CoV-2 and the Structural Basis of Its Intimate Binding. Front Immunol, 13, 2022
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