7WD2

Crystal structure of S43 bound to SARS-CoV-2 RBD

Summary for 7WD2

Entry DOI	10.2210/pdb7wd2/pdb
Descriptor	Spike protein S1, Anti-RON nanobody, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	sars-cov-2, rbd, s43, complex, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	4
Total formula weight	74378.37
Authors	Wang, Q.H.,Gao, G.F.,Qi, J.X.,Su, C.,Liu, H.H.,Wu, L.L. (deposition date: 2021-12-20, release date: 2022-12-21, Last modification date: 2023-11-29)
Primary citation	Liu, H.,Wu, L.,Liu, B.,Xu, K.,Lei, W.,Deng, J.,Rong, X.,Du, P.,Wang, L.,Wang, D.,Zhang, X.,Su, C.,Bi, Y.,Chen, H.,Liu, W.J.,Qi, J.,Cui, Q.,Qi, S.,Fan, R.,Jiang, J.,Wu, G.,Gao, G.F.,Wang, Q. Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice. Cell Rep Med, 4:100918-100918, 2023 Cited by PubMed: 36702124 DOI: 10.1016/j.xcrm.2023.100918 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.69 Å)

Structure validation