7LRZ

Structure of the Human ALK GRD

Summary for 7LRZ

Entry DOI	10.2210/pdb7lrz/pdb
Descriptor	ALK tyrosine kinase receptor (2 entities in total)
Functional Keywords	glycine rich domain, neuroblastoma, cancer, oncogene, signaling protein, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	31846.14
Authors	Stayrook, S.,Li, T.,Klein, D.E. (deposition date: 2021-02-17, release date: 2021-11-24, Last modification date: 2023-10-18)
Primary citation	Li, T.,Stayrook, S.E.,Tsutsui, Y.,Zhang, J.,Wang, Y.,Li, H.,Proffitt, A.,Krimmer, S.G.,Ahmed, M.,Belliveau, O.,Walker, I.X.,Mudumbi, K.C.,Suzuki, Y.,Lax, I.,Alvarado, D.,Lemmon, M.A.,Schlessinger, J.,Klein, D.E. Structural basis for ligand reception by anaplastic lymphoma kinase. Nature, 600:148-152, 2021 Cited by PubMed: 34819665 DOI: 10.1038/s41586-021-04141-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation