7WD1

Crystal structure of R14 bound to SARS-CoV-2 RBD

Summary for 7WD1

• Entry DOI: 10.2210/pdb7wd1/pdb
• Descriptor: Spike protein S1, R14, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: sars-cov-2, rbd, nanobody, complex, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 4
• Total formula weight: 73098.20

Authors

Wang, Q.H.,Gao, G.F.,Qi, J.X.,Su, C.,Liu, H.H.,Wu, L.L. (deposition date: 2021-12-20, release date: 2022-12-21, Last modification date: 2023-11-29)

• Primary citation: Liu, H.,Wu, L.,Liu, B.,Xu, K.,Lei, W.,Deng, J.,Rong, X.,Du, P.,Wang, L.,Wang, D.,Zhang, X.,Su, C.,Bi, Y.,Chen, H.,Liu, W.J.,Qi, J.,Cui, Q.,Qi, S.,Fan, R.,Jiang, J.,Wu, G.,Gao, G.F.,Wang, Q.; Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice.; Cell Rep Med, 4:100918-100918, 2023; PubMed: 36702124; DOI: 10.1016/j.xcrm.2023.100918

Experimental method

X-RAY DIFFRACTION (2.5 Å)