PDB: 19255 件ウェブページステータス検索Chemie searchBIRD

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8FPS	GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K) 分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-02-28 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.38 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ1	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150) 分子名称: CALCIUM ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-02-28 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (5.59 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8GMH	Crystal Structure of the ternary complex of TelA-LXG, LapA3, and LapA4 分子名称: 1,2-ETHANEDIOL, LXG domain-containing protein, LapA3, ... 著者 Klein, T.A, Shah, P.Y, Gkragkopoulou, P, Grebenc, D.W, Kim, Y, Whitney, J.C. 登録日 2023-03-25 公開日 2024-01-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of a tripartite protein complex that targets toxins to the type VII secretion system. Proc.Natl.Acad.Sci.USA, 121, 2024
8G10	Structure of Ternary Complex of cGAS with dsDNA and Bound ITP and GTP 分子名称: Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-02-01 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8G1J	Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and ITP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Wu, S, Sohn, J. 登録日 2023-02-02 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
6FID	Bovine trypsin solved by S-SAD on ID30B 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 McCarthy, A.A, Mueller-Dieckmann, C. 登録日 2018-01-18 公開日 2018-02-07 最終更新日 2018-08-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 ID30B - a versatile beamline for macromolecular crystallography experiments at the ESRF. J Synchrotron Radiat, 25, 2018
6FJ0	Crystal structure of ERK2 in complex with an adenosine derivative 分子名称: 5'-deoxy-5'-(prop-2-yn-1-ylamino)adenosine, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 Gelin, M, Labesse, G. 登録日 2018-01-19 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.659 Å) 主引用文献 Crystal structure of ERK2 in complex with an adenosine derivative To be published
6FJ6	Structure of Thaumatin collected at 100K on ID30B 分子名称: GLYCEROL, L(+)-TARTARIC ACID, Thaumatin-1 著者 McCarthy, A.A, Mueller-Dieckmann, C. 登録日 2018-01-20 公開日 2018-02-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 ID30B - a versatile beamline for macromolecular crystallography experiments at the ESRF. J Synchrotron Radiat, 25, 2018
8H0B	Structure of the thermolabile hemolysin from Vibrio alginolyticus (in complex with oleic acid) 分子名称: MAGNESIUM ION, OLEIC ACID, PENTAETHYLENE GLYCOL, ... 著者 Ma, Q, Wang, C. 登録日 2022-09-28 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.931 Å) 主引用文献 Catalytic site flexibility facilitates the substrate and catalytic promiscuity of Vibrio dual lipase/transferase. Nat Commun, 14, 2023
5NW8	Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp032 and Fasudil 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, UPF0418 protein FAM164A, ... 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2017-05-05 公開日 2018-05-30 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.086 Å) 主引用文献 Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019
8H0A	Structure of the thermolabile hemolysin from Vibrio alginolyticus (in complex with lauric acid) 分子名称: DI(HYDROXYETHYL)ETHER, LAURIC ACID, MAGNESIUM ION, ... 著者 Ma, Q, Wang, C. 登録日 2022-09-28 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Catalytic site flexibility facilitates the substrate and catalytic promiscuity of Vibrio dual lipase/transferase. Nat Commun, 14, 2023
6FK9	Crystal structure of N2C/D282C stabilized opsin bound to RS09 分子名称: (2~{S})-3-methyl-2-phenyl-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-butan-1-one, PALMITIC ACID, Rhodopsin, ... 著者 Mattle, D, Standfuss, J, Dawson, R. 登録日 2018-01-23 公開日 2018-04-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Ligand channel in pharmacologically stabilized rhodopsin. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8H09	Structure of the thermolabile hemolysin from Vibrio alginolyticus (apo form) 分子名称: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Ma, Q, Wang, C. 登録日 2022-09-28 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Catalytic site flexibility facilitates the substrate and catalytic promiscuity of Vibrio dual lipase/transferase. Nat Commun, 14, 2023
8H0C	Structure of the thermolabile hemolysin from Vibrio alginolyticus (in complex with arachidonic acid) 分子名称: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ARACHIDONIC ACID, MAGNESIUM ION, ... 著者 Ma, Q, Wang, C. 登録日 2022-09-28 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Catalytic site flexibility facilitates the substrate and catalytic promiscuity of Vibrio dual lipase/transferase. Nat Commun, 14, 2023
6FJ8	Structure of Thaumatin collected from an in situ crystal collected on ID30B at 12.7 keV. 分子名称: L(+)-TARTARIC ACID, Thaumatin-1 著者 McCarthy, A.A, Mueller-Dieckmann, C. 登録日 2018-01-21 公開日 2018-01-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 ID30B - a versatile beamline for macromolecular crystallography experiments at the ESRF. J Synchrotron Radiat, 25, 2018
8GUB	Cryo-EM structure of cancer-specific PI3Kalpha mutant H1047R in complex with BYL-719 分子名称: (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 著者 Liu, X, Zhou, Q, Hart, J.R, Xu, Y, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. 登録日 2022-09-11 公開日 2022-11-23 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.73 Å) 主引用文献 Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
8GVJ	Crystal structure of cMET kinase domain bound by D6808 分子名称: (1^4Z,5^2E)-6^3-(trifluoromethyl)-5^1,5^6-dihydro-1^1H-8-aza-2(3,6)-quinolina-5(1,3)-pyridazina-1(4,1)-pyrazola-6(1,4)-benzenacyclododecaphane-5^6,7-dione, Hepatocyte growth factor receptor 著者 Chen, Y.H, Qu, L.Z. 登録日 2022-09-15 公開日 2022-11-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J.Med.Chem., 65, 2022
8H0D	Structure of the thermolabile hemolysin from Vibrio alginolyticus (in complex with docosahexaenoic acid) 分子名称: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, MAGNESIUM ION, ... 著者 Ma, Q, Wang, C. 登録日 2022-09-28 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Catalytic site flexibility facilitates the substrate and catalytic promiscuity of Vibrio dual lipase/transferase. Nat Commun, 14, 2023
6FI3	Crystal structure of ERK2 in complex with an adenosine derivative 分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-(azanyloxymethyl)oxolane-3,4-diol, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 Gelin, M, Labesse, G. 登録日 2018-01-16 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Crystal structure of ERK2 in complex with an adenosine derivative To be published
6FJZ	Crystal structure of ERK2 in complex with an adenosine derivative 分子名称: (2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)-~{N}-prop-2-ynyl-oxolane-2-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION 著者 Gelin, M, Labesse, G. 登録日 2018-01-23 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.864 Å) 主引用文献 Crystal structure of ERK2 in complex with an adenosine derivative To be published
6FKB	Crystal structure of N2C/D282C stabilized opsin bound to RS13 分子名称: 2-(4-chlorophenyl)-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-ethanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... 著者 Mattle, D, Standfuss, J, Dawson, R. 登録日 2018-01-23 公開日 2018-04-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Ligand channel in pharmacologically stabilized rhodopsin. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8GNJ	Human SARM1 bounded with NMN and Nanobody-C6, Conformation 2 分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, NAD(+) hydrolase SARM1, Nanobody-C6 著者 Cai, Y, Zhang, H. 登録日 2022-08-24 公開日 2023-01-18 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 A conformation-specific nanobody targeting the nicotinamide mononucleotide-activated state of SARM1. Nat Commun, 13, 2022
8GNI	Human SARM1 bounded with NMN and Nanobody-C6, Conformation 1 分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, NAD(+) hydrolase SARM1, Nanobody C6 著者 Cai, Y, Zhang, H. 登録日 2022-08-24 公開日 2023-01-18 実験手法 ELECTRON MICROSCOPY (3.74 Å) 主引用文献 A conformation-specific nanobody targeting the nicotinamide mononucleotide-activated state of SARM1. Nat Commun, 13, 2022
8GQ5	Human SARM1 bounded with NMN and Nanobody-C6, double-layer structure 分子名称: NAD(+) hydrolase SARM1, Nanobody C6 著者 Cai, Y, Zhang, H. 登録日 2022-08-29 公開日 2023-01-18 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 A conformation-specific nanobody targeting the nicotinamide mononucleotide-activated state of SARM1. Nat Commun, 13, 2022
8GPN	Human menin in complex with H3K79Me2 nucleosome 分子名称: DNA (177-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Lin, J, Yu, D, Lam, W.H, Dang, S, Zhai, Y, Li, X.D. 登録日 2022-08-26 公開日 2023-02-15 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Menin "reads" H3K79me2 mark in a nucleosomal context. Science, 379, 2023

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