8GPN

Human menin in complex with H3K79Me2 nucleosome

Summary for 8GPN

• Entry DOI: 10.2210/pdb8gpn/pdb
• EMDB information: 34195
• Descriptor: Histone H3.2, Histone H4, Histone H2A type 1, ... (7 entities in total)
• Functional Keywords: specific histone modification reader, gene regulation
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 11
• Total formula weight: 286557.55

Authors

Lin, J.,Yu, D.,Lam, W.H.,Dang, S.,Zhai, Y.,Li, X.D. (deposition date: 2022-08-26, release date: 2023-02-15, Last modification date: 2023-03-01)

• Primary citation: Lin, J.,Wu, Y.,Tian, G.,Yu, D.,Yang, E.,Lam, W.H.,Liu, Z.,Jing, Y.,Dang, S.,Bao, X.,Wong, J.W.H.,Zhai, Y.,Li, X.D.; Menin "reads" H3K79me2 mark in a nucleosomal context.; Science, 379:717-723, 2023; PubMed: 36795828; DOI: 10.1126/science.adc9318

Experimental method

ELECTRON MICROSCOPY (3.2 Å)