8FPS
GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K)
Summary for 8FPS
| Entry DOI | 10.2210/pdb8fps/pdb |
| EMDB information | 29360 29369 |
| Descriptor | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | ionotropic glutamate receptor, ligand gated ion channel, ampa receptor, tarp gamma-2, transport protein |
| Biological source | Rattus norvegicus (Norway rat) More |
| Total number of polymer chains | 8 |
| Total formula weight | 546879.20 |
| Authors | Nakagawa, T. (deposition date: 2023-01-05, release date: 2024-02-28, Last modification date: 2024-03-13) |
| Primary citation | Nakagawa, T.,Wang, X.T.,Miguez-Cabello, F.J.,Bowie, D. The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38409505DOI: 10.1038/s41594-024-01228-3 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.38 Å) |
Structure validation
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