8FQ1

GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150)

Summary for 8FQ1

Entry DOI	10.2210/pdb8fq1/pdb
EMDB information	29360 29373
Descriptor	Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit, CALCIUM ION, ... (4 entities in total)
Functional Keywords	inotropic glutamate receptors, ampa receptors, ligand gated ion channel, auxiliary subunit, tarp, stargazin, tarp gamma2, glutamate, calcium, neurotransmitter receptor, synaptic transmission, transport protein
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	8
Total formula weight	547710.89
Authors	Nakagawa, T. (deposition date: 2023-01-05, release date: 2024-02-28, Last modification date: 2024-03-13)
Primary citation	Nakagawa, T.,Wang, X.T.,Miguez-Cabello, F.J.,Bowie, D. The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38409505 DOI: 10.1038/s41594-024-01228-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (5.59 Å)

Structure validation