PDB: 1550 件ウェブページステータス検索Chemie searchBIRD

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9F1C	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Yudin, D, Scaiola, A, Ban, N. 登録日 2024-04-18 公開日 2024-08-21 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
9BLN	The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex 分子名称: 40S ribosomal protein S14, ACETIC ACID, Eukaryotic initiation factor 4A-I, ... 著者 Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Zuber, P, Yifei, D, Albacete-Albacete, L, Ramakrishnan, V, S Fraser, C. 登録日 2024-04-30 公開日 2024-09-04 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit. Nat Commun, 15, 2024
9BKD	The structure of human Pdcd4 bound to the 40S small ribosomal subunit 分子名称: 18S rRNA, 40S ribosomal protein S12, 40S ribosomal protein S13, ... 著者 Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Zuber, P, Albacete-Albacete, L, Ramakrishnan, V, S.Fraser, C. 登録日 2024-04-27 公開日 2024-09-04 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit. Nat Commun, 15, 2024
7AI0	Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 1) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ... 著者 Magnussen, H.M, Huang, D.T. 登録日 2020-09-25 公開日 2021-01-20 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.559 Å) 主引用文献 Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. J.Mol.Biol., 433, 2021
9F1B	Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Yudin, D, Scaiola, A, Ban, N. 登録日 2024-04-18 公開日 2024-08-21 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
9F1D	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Yudin, D, Scaiola, A, Ban, N. 登録日 2024-04-18 公開日 2024-08-21 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
7AHZ	Crystal structure of Western clawed frog MDM2 RING domain homodimer bound to UbcH5B-Ub 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, ... 著者 Magnussen, H.M, Huang, D.T. 登録日 2020-09-25 公開日 2021-01-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. J.Mol.Biol., 433, 2021
7AI1	Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 2) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ... 著者 Magnussen, H.M, Huang, D.T. 登録日 2020-09-25 公開日 2021-01-20 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. J.Mol.Biol., 433, 2021
7B5N	Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1. 分子名称: 5-azanylpentan-2-one, Cullin-1, E3 ubiquitin-protein ligase ARIH1, ... 著者 Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2020-12-05 公開日 2021-02-10 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
7B5L	Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1 分子名称: 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ... 著者 Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2020-12-04 公開日 2021-02-10 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
7B5M	Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2 分子名称: Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... 著者 Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2020-12-05 公開日 2021-02-17 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
7ASE	43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase 分子名称: 18S, 40S ribosomal protein S10, putative, ... 著者 Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. 登録日 2020-10-27 公開日 2021-04-14 最終更新日 2021-04-21 実験手法 ELECTRON MICROSCOPY (3.33 Å) 主引用文献 Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
7AZY	Context-specific inhibition of eukaryotic translation by macrolide antibiotics 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Koller, T.O, Wilson, D.N. 登録日 2020-11-17 公開日 2021-05-19 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.877 Å) 主引用文献 Context-specific action of macrolide antibiotics on the eukaryotic ribosome. Nat Commun, 12, 2021
4Q5H	Shigella Effector Kinase OspG bound to AMPPNP and E2-Ub UbcH7-Ub Conjugate 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Polyubiquitin, ... 著者 Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2014-04-16 公開日 2014-07-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure, 22, 2014
4V88	The structure of the eukaryotic ribosome at 3.0 A resolution. 分子名称: 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ... 著者 Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M. 登録日 2011-10-11 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of the eukaryotic ribosome at 3.0 angstrom resolution. Science, 334, 2011
4Q5E	Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate 分子名称: Polyubiquitin, Protein kinase OspG, Ubiquitin-conjugating enzyme E2 L3 著者 Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2014-04-16 公開日 2014-07-02 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.869 Å) 主引用文献 Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure, 22, 2014
4V8P	T.thermophila 60S ribosomal subunit in complex with initiation factor 6. 分子名称: 26S RRNA, 5.8S RRNA, 5S RRNA, ... 著者 Klinge, S, Voigts-Hoffmann, F, Leibundgut, M, Arpagaus, S, Ban, N. 登録日 2011-09-14 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.52 Å) 主引用文献 Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6. Science, 334, 2011
4V8Z	Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex 分子名称: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... 著者 Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. 登録日 2013-07-20 公開日 2014-07-09 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Molecular architecture of a eukaryotic translational initiation complex. Science, 342, 2013
4V8M	High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome 分子名称: 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ... 著者 Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J. 登録日 2012-12-09 公開日 2014-07-09 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (5.57 Å) 主引用文献 High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome. Nature, 494, 2013
4V8Y	Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex 分子名称: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... 著者 Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. 登録日 2013-07-20 公開日 2014-07-09 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular architecture of a eukaryotic translational initiation complex. Science, 342, 2013
4R62	Structure of Rad6~Ub 分子名称: ACETATE ION, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 2 著者 Kumar, P, Wolberger, C. 登録日 2014-08-22 公開日 2015-09-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity. Nucleic Acids Res., 43, 2015
4UG0	STRUCTURE OF THE HUMAN 80S RIBOSOME 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ... 著者 Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P. 登録日 2015-03-20 公開日 2015-06-10 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the human 80S ribosome NATURE, 520, 2015
6VW2	Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils 分子名称: Islet amyloid polypeptide (SUMO-tagged) 著者 Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. 登録日 2020-02-18 公開日 2020-06-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils. Nat.Struct.Mol.Biol., 27, 2020
6W2T	Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the closed state (Class 2) 分子名称: 18S rRNA, CrPV 5'-UTR IRES, Eukaryotic translation initiation factor 3 subunit A, ... 著者 Neupane, R, Pisareva, V, Rodriguez, C.F, Pisarev, A, Fernandez, I.S. 登録日 2020-03-08 公開日 2020-04-22 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.36 Å) 主引用文献 A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate. Elife, 9, 2020
6WKR	PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome 分子名称: DNA (314-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Kasinath, V, Nogales, E, Beck, C, Sauer, P, Poepsel, S, Kosmatka, J, Faini, M, Toso, D, Aebersold, R. 登録日 2020-04-16 公開日 2021-02-03 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications. Science, 371, 2021

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