4Q5E

Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate

Summary for 4Q5E

Related4Q5H
DescriptorProtein kinase OspG, Polyubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... (4 entities in total)
Functional Keywordsprotein-protein complex, structural genomics, montreal-kingston bacterial structural genomics initiative, bsgi, kinase fold, inhibition of nf-kb pathway, unknown function, protein binding
Biological sourceShigella sonnei Ss046
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Cellular locationSecreted  Q3YTH2
Cytoplasm  P0CG63
Nucleus  P68036
Total number of polymer chains3
Total molecular weight46812.08
Authors
Cygler, M.,Grishin, A.M.,Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) (deposition date: 2014-04-16, release date: 2014-07-02, Last modification date: 2017-11-22)
Primary citation
Grishin, A.M.,Condos, T.E.,Barber, K.R.,Campbell-Valois, F.X.,Parsot, C.,Shaw, G.S.,Cygler, M.
Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG.
Structure, 22:878-888, 2014
PubMed: 24856362 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2014.04.010
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.869 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23350 0.3% 1.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-09-23