6WKR

PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome

Summary for 6WKR

• Entry DOI: 10.2210/pdb6wkr/pdb
• EMDB information: 21707
• Descriptor: Ubiquitin, Histone H4, Histone H2A type 1, ... (15 entities in total)
• Functional Keywords: chromatin, nucleosome, transcription, cryo-em, ubiquitination, gene regulation-dna complex, heterochromatin, dna binding, gene regulation/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 18
• Total formula weight: 623906.75

Authors

Kasinath, V.,Nogales, E.,Beck, C.,Sauer, P.,Poepsel, S.,Kosmatka, J.,Faini, M.,Toso, D.,Aebersold, R. (deposition date: 2020-04-16, release date: 2021-02-03)

• Primary citation: Kasinath, V.,Beck, C.,Sauer, P.,Poepsel, S.,Kosmatka, J.,Faini, M.,Toso, D.,Aebersold, R.,Nogales, E.; JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.; Science, 371:-, 2021; PubMed: 33479123; DOI: 10.1126/science.abc3393

Experimental method

ELECTRON MICROSCOPY (3.5 Å)