7AHZ

Crystal structure of Western clawed frog MDM2 RING domain homodimer bound to UbcH5B-Ub

This is a non-PDB format compatible entry.

Summary for 7AHZ

• Entry DOI: 10.2210/pdb7ahz/pdb
• Related: 6SQO
• Descriptor: E3 ubiquitin-protein ligase Mdm2, Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), Polyubiquitin-B, ... (6 entities in total)
• Functional Keywords: ubiquitin ligase, ring e3, ligase
• Biological source: Xenopus tropicalis (Western clawed frog); More
• Total number of polymer chains: 12
• Total formula weight: 135286.52

Authors

Magnussen, H.M.,Huang, D.T. (deposition date: 2020-09-25, release date: 2021-01-20, Last modification date: 2024-01-31)

• Primary citation: Magnussen, H.M.,Huang, D.T.; Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.; J.Mol.Biol., 433:166807-166807, 2021; PubMed: 33450248; DOI: 10.1016/j.jmb.2021.166807

Experimental method

X-RAY DIFFRACTION (1.82 Å)