7AHZ

Crystal structure of Western clawed frog MDM2 RING domain homodimer bound to UbcH5B-Ub

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0005634	cellular_component	nucleus
AAA	0042802	molecular_function	identical protein binding
AAA	0043066	biological_process	negative regulation of apoptotic process
AAA	0051726	biological_process	regulation of cell cycle
AAA	0061630	molecular_function	ubiquitin protein ligase activity
BBB	0005524	molecular_function	ATP binding
BBB	0016740	molecular_function	transferase activity
DDD	0005634	cellular_component	nucleus
DDD	0042802	molecular_function	identical protein binding
DDD	0043066	biological_process	negative regulation of apoptotic process
DDD	0051726	biological_process	regulation of cell cycle
DDD	0061630	molecular_function	ubiquitin protein ligase activity
EEE	0005524	molecular_function	ATP binding
EEE	0016740	molecular_function	transferase activity
GGG	0005634	cellular_component	nucleus
GGG	0042802	molecular_function	identical protein binding
GGG	0043066	biological_process	negative regulation of apoptotic process
GGG	0051726	biological_process	regulation of cell cycle
GGG	0061630	molecular_function	ubiquitin protein ligase activity
HHH	0005524	molecular_function	ATP binding
HHH	0016740	molecular_function	transferase activity
JJJ	0005634	cellular_component	nucleus
JJJ	0042802	molecular_function	identical protein binding
JJJ	0043066	biological_process	negative regulation of apoptotic process
JJJ	0051726	biological_process	regulation of cell cycle
JJJ	0061630	molecular_function	ubiquitin protein ligase activity
KKK	0005524	molecular_function	ATP binding
KKK	0016740	molecular_function	transferase activity

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
CCC	LYS27-ASP52

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: ADP-ribosylglycine => ECO:0000269\|PubMed:28525742

site_id	SWS_FT_FI2
Number of Residues	8
Details	CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)