6TKZ
 
 | |
6TGC
 | | CryoEM structure of the ternary DOCK2-ELMO1-RAC1 complex. | | 分子名称: | Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Chang, L, Yang, J, Chang, J.H, Zhang, Z, Boland, A, McLaughlin, S.H, Abu-Thuraia, A, Killoran, R.C, Smith, M.J, Cote, J.F, Barford, D. | | 登録日 | 2019-11-15 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
|
|
3CLV
 | | Crystal Structure of Rab5a from plasmodium falciparum, PFB0500c | | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Rab5 protein, ... | | 著者 | Chattopadhyay, D, Wernimont, A.K, Langsley, G, Lew, J, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Sukumar, D, Structural Genomics Consortium (SGC) | | 登録日 | 2008-03-20 | | 公開日 | 2008-07-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Crystal Structure of Rab5a from plasmodium falciparum, PFB0500c
To be Published
|
|
6OB3
 | | Crystal structure of G13D-KRAS (GMPPNP-bound) in complex with GAP-related domain (GRD) of neurofibromin (NF1) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GTPase KRas, ... | | 著者 | Tran, T.H, Dharmaiah, S, Simanshu, D.K. | | 登録日 | 2019-03-19 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6TVO
 | | Human CRM1-RanGTP in complex with Leptomycin B | | 分子名称: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Shaikhqasem, A, Ficner, R. | | 登録日 | 2020-01-10 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | | 主引用文献 | Characterization of Inhibition Reveals Distinctive Properties for Human andSaccharomyces cerevisiaeCRM1.
J.Med.Chem., 63, 2020
|
|
3GJ6
 | |
3GJ3
 | |
3GJ8
 | |
3GJ4
 | |
3GJ7
 | |
3GJ5
 | |
3GCG
 | | crystal structure of MAP and CDC42 complex | | 分子名称: | Cell division control protein 42 homolog, L0028 (Mitochondria associated protein) | | 著者 | Chai, J, Huang, Z, Feng, Y, Wu, X. | | 登録日 | 2009-02-22 | | 公開日 | 2009-07-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics
Nat.Struct.Mol.Biol., 16, 2009
|
|
4IRU
 | | Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3 | | 分子名称: | ACETATE ION, ALUMINUM FLUORIDE, GLYCEROL, ... | | 著者 | Mishra, A.K, Delcampo, C.M, Collins, R.E, Roy, C.R, Lambright, D.G. | | 登録日 | 2013-01-15 | | 公開日 | 2013-07-10 | | 最終更新日 | 2013-09-04 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism.
J.Biol.Chem., 288, 2013
|
|
4ITR
 | |
4JVS
 | | Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3 | | 分子名称: | ACETIC ACID, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Yu, Q, Yao, Q, Wang, D.-C, Shao, F. | | 登録日 | 2013-03-26 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.783 Å) | | 主引用文献 | Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP
Cell Res., 23, 2013
|
|
4K81
 | |
4I1O
 | | Crystal structure of the Legionella pneumophila GAP domain of LepB in complex with Rab1b bound to GDP and BeF3 | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Gazdag, E.M, Streller, A, Vetter, I.R, Goody, R.S, Itzen, A. | | 登録日 | 2012-11-21 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB.
Embo Rep., 14, 2013
|
|
4KYI
 | | Crystal structure of the phospholipase VipD from Legionella pneumophila in complex with the human GTPase Rab5 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Lucas, M, Gaspar, A.H, Pallara, C, Rojas, A.L, Fernandez-Recio, J, Machner, M.P, Hierro, A. | | 登録日 | 2013-05-29 | | 公開日 | 2014-08-13 | | 最終更新日 | 2015-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.075 Å) | | 主引用文献 | Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4KVG
 | | Crystal structure of RIAM RA-PH domains in complex with GTP bound Rap1 | | 分子名称: | 1,2-ETHANEDIOL, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Zhang, H, Chang, Y.E, Brennan, M.L, Wu, J. | | 登録日 | 2013-05-22 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanism.
J Mol Cell Biol, 6, 2014
|
|
4LHX
 | | Crystal structure of nucleotide-free Rab8:Rabin8 | | 分子名称: | Rab-3A-interacting protein, Ras-related protein Rab-8A, SULFATE ION | | 著者 | Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. | | 登録日 | 2013-07-01 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
|
|
4LI0
 | | Crystal structure of GDP-bound Rab8:GRAB | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide exchange factor for Rab-3A, Ras-related protein Rab-8A | | 著者 | Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. | | 登録日 | 2013-07-01 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
|
|
4LHZ
 | | Crystal structure of GTP-bound Rab8:Rabin8 | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Rab-3A-interacting protein, Ras-related protein Rab-8A | | 著者 | Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. | | 登録日 | 2013-07-01 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
|
|
4LHY
 | | Crystal structure of GDP-bound Rab8:Rabin8 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Rab-3A-interacting protein, Ras-related protein Rab-8A, ... | | 著者 | Guo, Z, Hou, X.M, Goody, R.S, Itzen, A. | | 登録日 | 2013-07-01 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.
J.Biol.Chem., 288, 2013
|
|
4M8N
 | | Crystal Structure of PlexinC1/Rap1B Complex | | 分子名称: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Pascoe, H.G, Wang, Y, Brautigam, C.A, He, H, Zhang, X. | | 登録日 | 2013-08-13 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.294 Å) | | 主引用文献 | Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin.
Elife, 2, 2013
|
|
4MIT
 | |
