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4O4U
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Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) mutant Trp-176-Ala from Haemophilus parasuis Hp5
分子名称: GLYCEROL, TbpB
著者Calmettes, C, Yu, R.H, Schryvers, A.B, Moraes, T.F.
登録日2013-12-19
公開日2015-01-14
最終更新日2015-03-04
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities.
Infect.Immun., 83, 2015
3GV5
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BU of 3gv5 by Molmil
Human DNA polymerase iota in complex with T template DNA and incoming ddADP
分子名称: 2',3'-DIDEOXYADENOSINE-5'-DIPHOSPHATE, 5'-D(*GP*TP*GP*GP*AP*TP*GP*AP*G)-3', 5'-D(P*CP*AP*TP*TP*CP*TP*CP*AP*TP*CP*CP*AP*C)-3', ...
著者Kirouac, K.N, Ling, H.
登録日2009-03-30
公開日2009-06-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota
Embo J., 28, 2009
3GVM
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Structure of the homodimeric WXG-100 family protein from Streptococcus agalactiae
分子名称: Putative uncharacterized protein SAG1039
著者Poulsen, C, Gries, F, Wilmanns, M, Song, Y.H.
登録日2009-03-31
公開日2010-09-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献WXG100 protein superfamily consists of three subfamilies and exhibits an alpha-helical C-terminal conserved residue pattern.
Plos One, 9, 2014
3GVW
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Single-chain UROD F217Y (YF) mutation
分子名称: Uroporphyrinogen decarboxylase
著者Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P.
登録日2009-03-31
公開日2009-12-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen.
J.Mol.Biol., 389, 2009
3HA9
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BU of 3ha9 by Molmil
The 1.7A Crystal Structure of a Thioredoxin-like Protein from Aeropyrum pernix
分子名称: uncharacterized Thioredoxin-like protein
著者Stein, A.J, Cuff, M.E, Sather, A, Hendricks, R, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-05-01
公開日2009-05-19
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The 1.7A Crystal Structure of a Thioredoxin-like Protein from Aeropyrum pernix
To be Published
3H9K
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Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry
分子名称: 1,2-ETHANEDIOL, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, PHOSPHATE ION, ...
著者Gibson, L.M, Lovelace, L.L, Lebioda, L.
登録日2009-04-30
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand binding.
Acta Crystallogr.,Sect.D, 67, 2011
2FS2
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BU of 2fs2 by Molmil
Structure of the E. coli PaaI protein from the phyenylacetic acid degradation operon
分子名称: Phenylacetic acid degradation protein paaI, SULFATE ION
著者Kniewel, R, Buglino, J.A, Solorzano, V, Wu, J, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-01-20
公開日2006-02-07
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure, Function, and Mechanism of the Phenylacetate Pathway Hot Dog-fold Thioesterase PaaI
J.Biol.Chem., 281, 2006
2FS8
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Human beta-tryptase II with inhibitor CRA-29382
分子名称: ALLYL {(1S)-1-[(5-{4-[(2,3-DIHYDRO-1H-INDEN-2-YLAMINO)CARBONYL]BENZYL}-1,2,4-OXADIAZOL-3-YL)CARBONYL]-3-PYRROLIDIN-3-YLPROPYL}CARBAMATE, Tryptase beta-2
著者Somoza, J.R.
登録日2006-01-21
公開日2006-03-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-guided design of Peptide-based tryptase inhibitors.
Biochemistry, 45, 2006
3UI4
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0.8 A resolution crystal structure of human Parvulin 14
分子名称: CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, SULFATE ION
著者Mueller, J.W, Link, N.M, Matena, A, Hoppstock, L, Rueppel, A, Bayer, P, Blankenfeldt, W.
登録日2011-11-04
公開日2011-12-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (0.8 Å)
主引用文献Crystallographic proof for an extended hydrogen-bonding network in small prolyl isomerases.
J.Am.Chem.Soc., 133, 2011
3H6K
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Crystal Structure of Human 11-beta-hydroxysteroid-dehydrogenase Bound to an Ortho-chlro-sulfonyl-piperazine Inhibitor
分子名称: 3-chloro-4-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl}sulfonyl)benzamide, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Bard, J, Svenson, K.
登録日2009-04-23
公開日2009-12-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.187 Å)
主引用文献Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model.
J.Med.Chem., 52, 2009
3UJS
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BU of 3ujs by Molmil
Asymmetric complex of human neuron specific enolase-6-PGA/PEP
分子名称: (2R)-2-(phosphonooxy)propanoic acid, (2R)-3-oxo-2-(phosphonooxy)propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L.
登録日2011-11-08
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
3ULJ
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BU of 3ulj by Molmil
Crystal structure of apo Lin28B cold shock domain
分子名称: ACETATE ION, GLYCEROL, Lin28b, ...
著者Mayr, F, Schuetz, A, Doege, N, Heinemann, U.
登録日2011-11-10
公開日2012-08-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献The Lin28 cold-shock domain remodels pre-let-7 microRNA.
Nucleic Acids Res., 40, 2012
4O94
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BU of 4o94 by Molmil
Crystal structure of a trap periplasmic solute binding protein from Rhodopseudomonas palustris HaA2 (RPB_3329), Target EFI-510223, with bound succinate
分子名称: CHLORIDE ION, SUCCINIC ACID, TRAP dicarboxylate transporter DctP subunit
著者Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2014-01-01
公開日2014-01-22
最終更新日2015-02-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Biochemistry, 54, 2015
3GLP
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BU of 3glp by Molmil
1.23 A resolution X-ray structure of (GCUGCUGC)2
分子名称: 5'-R(*GP*CP*UP*GP*CP*UP*GP*C)-3', GLYCEROL, SULFATE ION
著者Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W.
登録日2009-03-12
公開日2009-05-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Structural insights into CUG repeats containing the 'stretched U-U wobble': implications for myotonic dystrophy.
Nucleic Acids Res., 37, 2009
4O6M
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BU of 4o6m by Molmil
Structure of AF2299, a CDP-alcohol phosphotransferase (CMP-bound)
分子名称: AF2299, a CDP-alcohol phosphotransferase, CALCIUM ION, ...
著者Clarke, O.B, Sciara, G, Tomasek, D, Banerjee, S, Rajashankar, K.R, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2013-12-22
公開日2014-05-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Structural basis for catalysis in a CDP-alcohol phosphotransferase.
Nat Commun, 5, 2014
3UMZ
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BU of 3umz by Molmil
Crystal Structure of the human MDC1 FHA Domain
分子名称: Mediator of DNA damage checkpoint protein 1
著者Luo, S, Ye, K.
登録日2011-11-15
公開日2012-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3HAF
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BU of 3haf by Molmil
Human prion protein variant V129 domain swapped dimer
分子名称: CADMIUM ION, CHLORIDE ION, Major prion protein
著者Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
登録日2009-05-01
公開日2010-01-12
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HB7
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The Crystal Structure of an Isochorismatase-like Hydrolase from Alkaliphilus metalliredigens to 2.3A
分子名称: AMMONIUM ION, Isochorismatase hydrolase, SODIUM ION
著者Stein, A.J, Xu, X, Cui, H, Ng, J, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-05-04
公開日2009-07-07
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of an Isochorismatase-like Hydrolase from Alkaliphilus metalliredigens to 2.3A
To be Published
4OGK
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X-ray structure of the uridine phosphorylase from Salmonella typhimurium in complex with thymidine at 2.40 A resolution
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ISOPROPYL ALCOHOL, ...
著者Sotnichenko, S.E, Lashkov, A.A, Gabdoulkhakov, A.G, Mikhailov, A.M.
登録日2014-01-16
公開日2015-03-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray structure of the uridine phosphorylase from Salmonella typhimurium in complex with thymidine at 2.40 A resolution
To be Published
3UI5
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Crystal structure of human Parvulin 14
分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, SODIUM ION, ...
著者Mueller, J.W, Link, N.M, Matena, A, Hoppstock, L, Rueppel, A, Bayer, P, Blankenfeldt, W.
登録日2011-11-04
公開日2011-12-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystallographic proof for an extended hydrogen-bonding network in small prolyl isomerases.
J.Am.Chem.Soc., 133, 2011
3UGV
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Crystal structure of an enolase from alpha pretobacterium bal199 (EFI TARGET EFI-501650) with bound MG
分子名称: CHLORIDE ION, Enolase, MAGNESIUM ION, ...
著者Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2011-11-03
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of an enolase from alpha pretobacterium bal199 (EFI TARGET EFI-501650) with bound MG
to be published
3UKF
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CRYSTAL STRUCTURE OF UDP-galactopyranose mutase from Aspergillus fumigatus in complex with UDPgalp (reduced)
分子名称: CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ...
著者Van Straaten, K.E, Sanders, D.A.R.
登録日2011-11-09
公開日2012-02-22
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus.
J.Biol.Chem., 287, 2012
2G3N
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Crystal structure of the Sulfolobus solfataricus alpha-glucosidase MalA in complex with beta-octyl-glucopyranoside
分子名称: Alpha-glucosidase, octyl beta-D-glucopyranoside
著者Ernst, H.A, Lo Leggio, L, Willemoes, M, Leonard, G, Blum, P, Larsen, S.
登録日2006-02-20
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of the Sulfolobus solfataricus alpha-Glucosidase: Implications for Domain Conservation and Substrate Recognition in GH31.
J.Mol.Biol., 358, 2006
4OE6
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Crystal Structure of Yeast ALDH4A1
分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
著者Tanner, J.J.
登録日2014-01-11
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.951 Å)
主引用文献Structural Studies of Yeast Delta (1)-Pyrroline-5-carboxylate Dehydrogenase (ALDH4A1): Active Site Flexibility and Oligomeric State.
Biochemistry, 53, 2014
4OK3
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Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 7 [[1-(3-chlorobenzyl)-1H-indol-3-yl]acetic acid]
分子名称: CALCIUM ION, Serine protease NS3, [1-(3-chlorobenzyl)-1H-indol-3-yl]acetic acid
著者Padyana, A.K.
登録日2014-01-21
公開日2014-03-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus.
J.Med.Chem., 57, 2014

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