3GV5
Human DNA polymerase iota in complex with T template DNA and incoming ddADP
Summary for 3GV5
Entry DOI | 10.2210/pdb3gv5/pdb |
Related | 3GV7 3GV8 |
Descriptor | DNA polymerase iota, 5'-D(*GP*TP*GP*GP*AP*TP*GP*AP*G)-3', 5'-D(P*CP*AP*TP*TP*CP*TP*CP*AP*TP*CP*CP*AP*C)-3', ... (7 entities in total) |
Functional Keywords | y-family polymerase, polymerase iota, error prone replication, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, nucleus, schiff base, transferase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9UNA4 |
Total number of polymer chains | 6 |
Total formula weight | 109748.08 |
Authors | Kirouac, K.N.,Ling, H. (deposition date: 2009-03-30, release date: 2009-06-02, Last modification date: 2017-11-01) |
Primary citation | Kirouac, K.N.,Ling, H. Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota Embo J., 28:1644-1654, 2009 Cited by PubMed: 19440206DOI: 10.1038/emboj.2009.122 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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