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3GVW

Single-chain UROD F217Y (YF) mutation

Summary for 3GVW
Entry DOI10.2210/pdb3gvw/pdb
Related1uro 3GVQ 3GVR 3GVV
DescriptorUroporphyrinogen decarboxylase (2 entities in total)
Functional Keywordsuroporphyrinogen, decarboxylase, lyase, heme biosynthesis, acetylation, cytoplasm, disease mutation, phosphoprotein, porphyrin biosynthesis
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm: P06132
Total number of polymer chains1
Total formula weight40847.77
Authors
Hill, C.P.,Phillips, J.D.,Whitby, F.G.,Warby, C.,Kushner, J.P. (deposition date: 2009-03-31, release date: 2009-12-22, Last modification date: 2024-02-21)
Primary citationPhillips, J.D.,Warby, C.A.,Whitby, F.G.,Kushner, J.P.,Hill, C.P.
Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen.
J.Mol.Biol., 389:306-314, 2009
Cited by
PubMed: 19362562
DOI: 10.1016/j.jmb.2009.04.013
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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