7EC3
 
 | | Crystal structure of SdgB (complexed with UDP, GlcNAc, and Glycosylated peptide) | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-35)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-65)]5,6-DIHYDRO-BENZO[H]CINNOLIN-3-YLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosyl transferase, ... | | 著者 | Kim, D.-G, Baek, I, Lee, Y, Kim, H.S. | | 登録日 | 2021-03-11 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for SdgB- and SdgA-mediated glycosylation of staphylococcal adhesive proteins.
Acta Crystallogr D Struct Biol, 77, 2021
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7EN3
 | | Crystal structure of tubulin in complex with Tubulysin analogue TGL | | 分子名称: | (2S,4R)-5-(4-fluorophenyl)-2-methyl-4-[[2-[(1R,3R)-4-methyl-3-[5-methylhexyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]-1-oxidanyl-pentyl]-1,3-thiazol-4-yl]carbonylamino]pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wang, Y, Li, W. | | 登録日 | 2021-04-15 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.643 Å) | | 主引用文献 | The X-ray structure of tubulysin analogue TGL in complex with tubulin and three possible routes for the development of next-generation tubulysin analogues.
Biochem.Biophys.Res.Commun., 565, 2021
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7ENO
 | | Mutant strain M3 of foot-and-mouth disease virus type O | | 分子名称: | VP1 of O type FMDV capsid, VP2 of O type FMDV capsid, VP3 of O type FMDV capsid, ... | | 著者 | Dong, H, Lu, Y. | | 登録日 | 2021-04-18 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | A Heat-Induced Mutation on VP1 of Foot-and-Mouth Disease Virus Serotype O Enhanced Capsid Stability and Immunogenicity.
J.Virol., 95, 2021
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7ENP
 | | wild type of O type Foot-and-mouth disease virus | | 分子名称: | VP1 of O type FMDV capsid protein, VP2 of O type FMDV capsid protein, VP3 of O type FMDV capsid protein, ... | | 著者 | Dong, H, Lu, Y. | | 登録日 | 2021-04-18 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | A Heat-Induced Mutation on VP1 of Foot-and-Mouth Disease Virus Serotype O Enhanced Capsid Stability and Immunogenicity.
J.Virol., 95, 2021
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7EC1
 | | Crystal structure of SdgB (ligand-free form) | | 分子名称: | GLYCEROL, Glycosyl transferase, group 1 family protein, ... | | 著者 | Kim, D.-G, Baek, I, Lee, Y, Kim, H.S. | | 登録日 | 2021-03-11 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis for SdgB- and SdgA-mediated glycosylation of staphylococcal adhesive proteins.
Acta Crystallogr D Struct Biol, 77, 2021
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7E9H
 | | Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu4 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-3, ... | | 著者 | Lin, S, Han, S, Zhao, Q, Wu, B. | | 登録日 | 2021-03-04 | | 公開日 | 2021-06-23 | | 最終更新日 | 2021-07-07 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures of G i -bound metabotropic glutamate receptors mGlu2 and mGlu4.
Nature, 594, 2021
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7FCI
 | | human NTCP in complex with YN69083 Fab | | 分子名称: | Fab Heavy chain, Fab Light chain, Sodium/bile acid cotransporter | | 著者 | Park, J.H, Iwamoto, M, Yun, J.H, Uchikubo-Kamo, T, Son, D, Jin, Z, Yoshida, H, Ohki, M, Ishimoto, N, Mizutani, K, Oshima, M, Muramatsu, M, Wakita, T, Shirouzu, M, Liu, K, Uemura, T, Nomura, N, Iwata, S, Watashi, K, Tame, J.R.H, Nishizawa, T, Lee, W, Park, S.Y. | | 登録日 | 2021-07-14 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into the HBV receptor and bile acid transporter NTCP.
Nature, 606, 2022
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7CYC
 | | Cryo-EM structures of Alphacoronavirus spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Song, X, Shi, Y, Ding, W, Liu, Z.J, Peng, G. | | 登録日 | 2020-09-03 | | 公開日 | 2020-12-23 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes.
Nat Commun, 12, 2021
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7CYD
 | | Cryo-EM structures of Alphacoronavirus spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Song, X, Shi, Y, Ding, W, Liu, Z.J, Peng, G. | | 登録日 | 2020-09-03 | | 公開日 | 2020-12-23 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes.
Nat Commun, 12, 2021
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7EOW
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7FJC
 | | Crystal structure of SARS-CoV-2 Beta RBD complexed with P36-5D2 Fab | | 分子名称: | P36-5D2 heavy chain, P36-5D2 light chain, Spike protein S1, ... | | 著者 | Zhang, L.Q, Wang, X.Q, Shan, S.S, Lan, J. | | 登録日 | 2021-08-03 | | 公開日 | 2022-08-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Crystal structure of SARS-CoV-2 Beta RBD complexed with P36-5D2 Fab
To Be Published
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7D6I
 | | A neutralizing MAb targeting receptor-binding-domain of SARS-CoV-2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of GH12-Fab, Light chain of GH12-Fab, ... | | 著者 | Shi, R, Qi, J.X, Gao, G.F, Yan, J.H. | | 登録日 | 2020-09-30 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | A neutralizing MAb targeting receptor-binding-domain of SARS-CoV-2
To Be Published
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7C2S
 | | Helical reconstruction of Dengue virus serotype 3 complexed with Fab C10 | | 分子名称: | Heavy chain of Fab C10, envelope protein, light chain of Fab C10 | | 著者 | Morrone, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Zhang, S, Lok, S.M. | | 登録日 | 2020-05-09 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (10.4 Å) | | 主引用文献 | High flavivirus structural plasticity demonstrated by a non-spherical morphological variant.
Nat Commun, 11, 2020
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7CN2
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7C2T
 | | Helical reconstruction of Zika virus complexed with Fab C10 | | 分子名称: | Heavy chain from Fab C10, Light chain from Fab C10, M protein, ... | | 著者 | Morrone, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Zhang, S, Lok, S.M. | | 登録日 | 2020-05-09 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | | 主引用文献 | High flavivirus structural plasticity demonstrated by a non-spherical morphological variant.
Nat Commun, 11, 2020
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7FBI
 | | Cryo-EM structure of EBV gB in complex with nAbs 3A3 and 3A5 | | 分子名称: | 3A3 heavy chain, 3A3 light chain, 3A5 heavy chain, ... | | 著者 | Zheng, Q, Li, S, Zha, Z, Hong, J, Chen, Y, Zhang, X. | | 登録日 | 2021-07-10 | | 公開日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structure of EBV gB in complex with nAbs 3A3 and 3A5
To Be Published
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6OGE
 | | Cryo-EM structure of Her2 extracellular domain-Trastuzumab Fab-Pertuzumab Fab complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab FAB HEAVY CHAIN, Pertuzumab FAB LIGHT CHAIN, ... | | 著者 | Hao, Y, Yu, X, Bai, Y, Huang, X. | | 登録日 | 2019-04-02 | | 公開日 | 2019-05-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.36 Å) | | 主引用文献 | Cryo-EM Structure of HER2-trastuzumab-pertuzumab complex.
Plos One, 14, 2019
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7K60
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7JO8
 | | Crystal structure of a Chimeric Antigen Receptor (CAR) scFv domain rearrangement forming a VL-VL dimer | | 分子名称: | 47G4-CD828Z, MALONATE ION, PENTAETHYLENE GLYCOL, ... | | 著者 | Cheung, J, Hendrickson, W.A, Kochenderfer, J.N, Youkharibache, P. | | 登録日 | 2020-08-06 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | | 主引用文献 | Crystal Structure of a Chimeric Antigen Receptor (CAR) scFv Domain Rearrangement Forming a VL-VL Dimer
Crystals, 13, 2023
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7KDP
 | | HCMV prefusion gB in complex with fusion inhibitor WAY-174865 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein B, ... | | 著者 | Liu, Y, Heim, P.K, Che, Y, Chi, X, Qiu, X, Han, S, Dormitzer, P.R, Yang, X. | | 登録日 | 2020-10-09 | | 公開日 | 2021-03-17 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion.
Sci Adv, 7, 2021
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7K0Z
 | | Marsupial T cell receptor Spl_157 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, T cell receptor gamma chain, T cell receptor mu chain | | 著者 | Wegrecki, M, Kannan Sivaraman, K, Le Nours, J, Rossjohn, J. | | 登録日 | 2020-09-06 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The molecular assembly of the marsupial gamma mu T cell receptor defines a third T cell lineage.
Science, 371, 2021
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7K0X
 | | Marsupial T cell receptor Spl_145 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, T cell receptor gamma chain, T cell receptor mu chain, ... | | 著者 | Wegrecki, M, Kannan Sivaraman, K, Le Nours, J, Rossjohn, J. | | 登録日 | 2020-09-06 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The molecular assembly of the marsupial gamma mu T cell receptor defines a third T cell lineage.
Science, 371, 2021
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7KD6
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7KZX
 | | Cryo-EM structure of YiiP-Fab complex in Apo state | | 分子名称: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain | | 著者 | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | | 登録日 | 2020-12-10 | | 公開日 | 2021-01-06 | | 最終更新日 | 2021-07-28 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP.
J.Gen.Physiol., 153, 2021
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7KZZ
 | | Cryo-EM structure of YiiP-Fab complex in Holo state | | 分子名称: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain, ... | | 著者 | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | | 登録日 | 2020-12-10 | | 公開日 | 2021-01-06 | | 最終更新日 | 2021-07-28 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP.
J.Gen.Physiol., 153, 2021
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