7JO8

Crystal structure of a Chimeric Antigen Receptor (CAR) scFv domain rearrangement forming a VL-VL dimer

Summary for 7JO8

Entry DOI	10.2210/pdb7jo8/pdb
Descriptor	47G4-CD828Z, PENTAETHYLENE GLYCOL, MALONATE ION, ... (5 entities in total)
Functional Keywords	chimeric antigen receptor (car) antibody scfv rearrangement vl-vl complex, immune system
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	24148.67
Authors	Cheung, J.,Hendrickson, W.A.,Kochenderfer, J.N.,Youkharibache, P. (deposition date: 2020-08-06, release date: 2021-02-10, Last modification date: 2023-10-25)
Primary citation	Cheung, J.,Wazir, S.,Bell, D.R.,Kochenderfer, J.N.,Hendrickson, W.A.,Youkharibache, P. Crystal Structure of a Chimeric Antigen Receptor (CAR) scFv Domain Rearrangement Forming a VL-VL Dimer Crystals, 13:-, 2023 Cited by DOI: 10.3390/cryst13040710 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.399 Å)

Structure validation