7CYC

Cryo-EM structures of Alphacoronavirus spike glycoprotein

Replaces:  6IXA

Summary for 7CYC

• Entry DOI: 10.2210/pdb7cyc/pdb
• EMDB information: 30496
• Descriptor: Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: alphacoronavirus, spike glycoprotein, structural protein
• Biological source: Human coronavirus 229E (HCoV-229E)
• Total number of polymer chains: 3
• Total formula weight: 386321.78

Authors

Song, X.,Shi, Y.,Ding, W.,Liu, Z.J.,Peng, G. (deposition date: 2020-09-03, release date: 2020-12-23, Last modification date: 2021-06-02)

• Primary citation: Song, X.,Shi, Y.,Ding, W.,Niu, T.,Sun, L.,Tan, Y.,Chen, Y.,Shi, J.,Xiong, Q.,Huang, X.,Xiao, S.,Zhu, Y.,Cheng, C.,Fu, Z.F.,Liu, Z.J.,Peng, G.; Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes.; Nat Commun, 12:141-141, 2021; PubMed: 33420048; DOI: 10.1038/s41467-020-20401-y

Experimental method

ELECTRON MICROSCOPY (3.21 Å)