1FX8
| CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITH SUBSTRATE GLYCEROL | 分子名称: | GLYCEROL, GLYCEROL UPTAKE FACILITATOR PROTEIN, octyl beta-D-glucopyranoside | 著者 | Fu, D, Libson, A, Miercke, L.J.W, Weitzman, C, Nollert, P, Stroud, R.M. | 登録日 | 2000-09-25 | 公開日 | 2000-11-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of a glycerol-conducting channel and the basis for its selectivity. Science, 290, 2000
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2Y96
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2FDM
| Crystal structure of the ternary complex of signalling glycoprotein frm sheep (SPS-40)with hexasaccharide (NAG6) and peptide Trp-Pro-Trp at 3.0A resolution | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Chitinase-3-like protein 1, ... | 著者 | Srivastava, D.B, Ethayathulla, A.S, Kumar, J, Somvanshi, R.K, Sharma, S, Singh, T.P. | 登録日 | 2005-12-14 | 公開日 | 2006-01-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the ternary complex of signalling glycoprotein frm sheep (SPS-40)
with hexasaccharide (NAG6) and peptide Trp-Pro-Trp at 3.0A resolution To be Published
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1G5K
| NMR Structrure of d(CCAAAGXACTGGG), X is a 3'-phosphoglycolate, 5'-phosphate gapped lesion, 10 structures | 分子名称: | 2-PHOSPHOGLYCOLIC ACID, 5'-D(*CP*CP*AP*AP*AP*G)-3', 5'-D(*CP*CP*CP*AP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3', ... | 著者 | Junker, H.-D, Hoehn, S.T, Bunt, R.C, Marathius, V, Chen, J, Turner, C.J, Stubbe, J. | 登録日 | 2002-10-14 | 公開日 | 2003-01-07 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Synthesis, Characterization and Solution Structure of Tethered Oligonucleotides Containing an Internal 3'-Phosphoglycolate, 5'-Phosphate Gapped Lesion Nucleic Acids Res., 30, 2002
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4ISG
| Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-[4-(methylsulfonyl)-2-oxopiperazin-1-yl]-N-(1,3-thiazol-2-yl)propanamide | 分子名称: | (2S)-3-cyclohexyl-2-[4-(methylsulfonyl)-2-oxopiperazin-1-yl]-N-(1,3-thiazol-2-yl)propanamide, Glucokinase, IODIDE ION, ... | 著者 | Hosfield, D, Skene, R.J. | 登録日 | 2013-01-16 | 公開日 | 2013-03-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.645 Å) | 主引用文献 | Design, synthesis and SAR of novel glucokinase activators. Bioorg.Med.Chem.Lett., 23, 2013
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6MV1
| 2.15A resolution structure of the CS-b5R domains of human Ncb5or (NAD+ form) | 分子名称: | Cytochrome b5 reductase 4, FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Benson, D.R, Cooper, A, Gao, P, Zhu, H. | 登録日 | 2018-10-24 | 公開日 | 2019-07-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structures of the naturally fused CS and cytochrome b5reductase (b5R) domains of Ncb5or reveal an expanded CS fold, extensive CS-b5R interactions and productive binding of the NAD(P)+nicotinamide ring. Acta Crystallogr D Struct Biol, 75, 2019
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1GH0
| CRYSTAL STRUCTURE OF C-PHYCOCYANIN FROM SPIRULINA PLATENSIS | 分子名称: | C-PHYCOCYANIN ALPHA SUBUNIT, C-PHYCOCYANIN BETA SUBUNIT, PHYCOCYANOBILIN | 著者 | Liang, D.-C, Chang, W.-R, Wang, X.-Q. | 登録日 | 2000-10-29 | 公開日 | 2001-06-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of C-phycocyanin from Spirulina platensis at 2.2 A resolution: a novel monoclinic crystal form for phycobiliproteins in phycobilisomes. Acta Crystallogr.,Sect.D, 57, 2001
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1G14
| NMR SOLUTION STRUCTURE OF THE DNA DODECAMER GGCAAGAAACGG | 分子名称: | 5'-D(*CP*CP*GP*TP*TP*TP*CP*TP*TP*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*AP*GP*AP*AP*AP*CP*GP*G)-3' | 著者 | MacDonald, D, Herbert, K, Zhang, X, Pologruto, T, Lu, P. | 登録日 | 2000-10-10 | 公開日 | 2001-03-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of an A-tract DNA bend. J.Mol.Biol., 306, 2001
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4D1D
| STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER with the inhibitor 5-(2-naphthylmethyl)-L-hydantoin. | 分子名称: | 5-(2-NAPHTHYLMETHYL)-D-HYDANTOIN, 5-(2-NAPHTHYLMETHYL)-L-HYDANTOIN, HYDANTOIN TRANSPORT PROTEIN, ... | 著者 | Weyand, S, Brueckner, F, Geng, T, Drew, D, Iwata, S, Henderson, P.J.F, Cameron, A.D. | 登録日 | 2014-05-01 | 公開日 | 2014-07-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1. Embo J., 33, 2014
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1MCK
| PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | 分子名称: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-D-GLU-L-HIS-D-PRO-NH2 | 著者 | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | 登録日 | 1993-02-25 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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302D
| META-HYDROXY ANALOGUE OF HOECHST 33258 ('HYDROXYL IN' CONFORMATION) BOUND TO D(CGCGAATTCGCG)2 | 分子名称: | 3-[5-[5-(4-METHYL-PIPERAZIN-1-YL)-1H-IMIDAZO[4,5-B]PYRIDIN-2-YL]-BENZIMIDAZOL-2-YL]-PHENOL, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | 著者 | Clark, G.R, Squire, C.J, Gray, E.J, Leupin, W, Neidle, S. | 登録日 | 1996-06-26 | 公開日 | 1997-01-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Designer DNA-binding drugs: the crystal structure of a meta-hydroxy analogue of Hoechst 33258 bound to d(CGCGAATTCGCG)2. Nucleic Acids Res., 24, 1996
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1Q55
| W-shaped trans interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | He, W, Cowin, P, Stokes, D.L. | 登録日 | 2003-08-06 | 公開日 | 2003-10-07 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (30 Å) | 主引用文献 | Untangling Desmosomal Knots with Electron Tomography Science, 302, 2003
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1DMT
| STRUCTURE OF HUMAN NEUTRAL ENDOPEPTIDASE COMPLEXED WITH PHOSPHORAMIDON | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ... | 著者 | Oefner, C, D'Arcy, A, Hennig, M, Winkler, F.K, Dale, G.E. | 登録日 | 1999-12-15 | 公開日 | 2000-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon. J.Mol.Biol., 296, 2000
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4OTV
| Crystal structure of in cellulo Operophtera brumata CPV18 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Stuart, D.I, Sutton, G.C, Axford, D, Ji, X. | 登録日 | 2014-02-14 | 公開日 | 2014-05-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | In cellulo structure determination of a novel cypovirus polyhedrin. Acta Crystallogr.,Sect.D, 70, 2014
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1DX5
| Crystal structure of the thrombin-thrombomodulin complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FORMIC ACID, ... | 著者 | Fuentes-Prior, P, Iwanaga, Y, Huber, R, Pagila, R, Rumennik, G, Seto, M, Morser, J, Light, D.R, Bode, W. | 登録日 | 1999-12-20 | 公開日 | 2000-04-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex Nature, 404, 2000
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4FEW
| Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP2 | 分子名称: | 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, ... | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-05-30 | 公開日 | 2012-06-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem.J., 454, 2013
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1X70
| HUMAN DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH A BETA AMINO ACID INHIBITOR | 分子名称: | (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-A MINE, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kim, D, Wang, L, Beconi, M, Eiermann, G.J, Fisher, M.H, He, H, Hickey, G.J, Leiting, B, Lyons, K. | 登録日 | 2004-08-12 | 公開日 | 2005-01-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | (2R)-4-Oxo-4-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes J.Med.Chem., 48, 2005
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6MV2
| 2.05A resolution structure of the CS-b5R domains of human Ncb5or (NADP+ form) | 分子名称: | Cytochrome b5 reductase 4, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Benson, D.R, Cooper, A, Gao, P, Zhu, H. | 登録日 | 2018-10-24 | 公開日 | 2019-07-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structures of the naturally fused CS and cytochrome b5reductase (b5R) domains of Ncb5or reveal an expanded CS fold, extensive CS-b5R interactions and productive binding of the NAD(P)+nicotinamide ring. Acta Crystallogr D Struct Biol, 75, 2019
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6MVL
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3TE1
| Crystal structure of HSC T84A | 分子名称: | TETRAETHYLENE GLYCOL, formate/nitrite transporter, octyl beta-D-glucopyranoside | 著者 | Czyzewski, B.K, Wang, D.-N. | 登録日 | 2011-08-11 | 公開日 | 2012-03-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Identification and characterization of a bacterial hydrosulphide ion channel. Nature, 483, 2012
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3TDP
| Crystal structure of HSC at pH 4.5 | 分子名称: | ZINC ION, formate/nitrite transporter, octyl beta-D-glucopyranoside | 著者 | Czyzewski, B.K, Wang, D.-N. | 登録日 | 2011-08-11 | 公開日 | 2012-03-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Identification and characterization of a bacterial hydrosulphide ion channel. Nature, 483, 2012
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1RDH
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1RFG
| Crystal Structure of Human Purine Nucleoside Phosphorylase Complexed with Guanosine | 分子名称: | GUANOSINE, Purine nucleoside phosphorylase, SULFATE ION | 著者 | Canduri, F, Silva, R.G, Dos Santos, D.M, Palma, M.S, Basso, L.A, Santos, D.S, de Azevedo, W.F. | 登録日 | 2003-11-09 | 公開日 | 2004-12-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of human PNP complexed with ligands. Acta Crystallogr.,Sect.D, 61, 2005
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3U7U
| Crystal structure of extracellular region of human epidermal growth factor receptor 4 in complex with neuregulin-1 beta | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuregulin 1, Receptor tyrosine-protein kinase erbB-4 | 著者 | Liu, P, Cleveland IV, T.E, Bouyain, S, Longo, P.A, Leahy, D.J. | 登録日 | 2011-10-14 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | A single ligand is sufficient to activate EGFR dimers. Proc.Natl.Acad.Sci.USA, 109, 2012
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2AKR
| Structural basis of sulfatide presentation by mouse CD1d | 分子名称: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zajonc, D.M, Halder, R, Wu, D, Maricic, I, Roy, K, Wong, C.-H, Kumar, V, Wilson, I.A. | 登録日 | 2005-08-03 | 公開日 | 2005-12-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity J.Exp.Med., 202, 2005
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