1DX5

Crystal structure of the thrombin-thrombomodulin complex

Summary for 1DX5
Related PRD IDPRD_000288
DescriptorThrombin light chain, Thrombomodulin, Thrombin heavy chain, ... (9 entities in total)
Functional Keywordsserine proteinase, egf-like domains, anticoagulant complex, antifibrinolytic complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains12
Total formula weight194112.57
Authors
Fuentes-Prior, P.,Iwanaga, Y.,Huber, R.,Pagila, R.,Rumennik, G.,Seto, M.,Morser, J.,Light, D.R.,Bode, W. (deposition date: 1999-12-20, release date: 2000-04-10, Last modification date: 2020-07-29)
Primary citationBode, W.,Fuentes-Prior, P.,Huber, R.,Iwanaga, Y.,Light, D.R.,Morser, J.,Pagila, R.,Rumennik, G.,Seto, M.
Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex
Nature, 404:518-, 2000
PubMed: 10761923
DOI: 110.1038/35006683
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation
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PDB entries from 2021-06-09