1DX5
Crystal structure of the thrombin-thrombomodulin complex
Summary for 1DX5
Entry DOI | 10.2210/pdb1dx5/pdb |
Related PRD ID | PRD_000288 |
Descriptor | Thrombin light chain, Thrombomodulin, Thrombin heavy chain, ... (9 entities in total) |
Functional Keywords | serine proteinase, egf-like domains, anticoagulant complex, antifibrinolytic complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 194112.57 |
Authors | Fuentes-Prior, P.,Iwanaga, Y.,Huber, R.,Pagila, R.,Rumennik, G.,Seto, M.,Morser, J.,Light, D.R.,Bode, W. (deposition date: 1999-12-20, release date: 2000-04-10, Last modification date: 2024-05-01) |
Primary citation | Fuentes-Prior, P.,Iwanaga, Y.,Huber, R.,Pagila, R.,Rumennik, G.,Seto, M.,Morser, J.,Light, D.R.,Bode, W. Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex Nature, 404:518-, 2000 Cited by PubMed: 10761923DOI: 10.1038/35006683 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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