6MV2
2.05A resolution structure of the CS-b5R domains of human Ncb5or (NADP+ form)
Summary for 6MV2
Entry DOI | 10.2210/pdb6mv2/pdb |
Descriptor | Cytochrome b5 reductase 4, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
Functional Keywords | ncb5or, electron transfer, redox, heme, endoplasmic reticulum, flavoprotein, iron, metal-binding, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 43648.46 |
Authors | Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Benson, D.R.,Cooper, A.,Gao, P.,Zhu, H. (deposition date: 2018-10-24, release date: 2019-07-17, Last modification date: 2023-10-11) |
Primary citation | Benson, D.R.,Lovell, S.,Mehzabeen, N.,Galeva, N.,Cooper, A.,Gao, P.,Battaile, K.P.,Zhu, H. Crystal structures of the naturally fused CS and cytochrome b5reductase (b5R) domains of Ncb5or reveal an expanded CS fold, extensive CS-b5R interactions and productive binding of the NAD(P)+nicotinamide ring. Acta Crystallogr D Struct Biol, 75:628-638, 2019 Cited by PubMed: 31282472DOI: 10.1107/S205979831900754X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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