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6ZU9
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BU of 6zu9 by Molmil
Structure of a yeast ABCE1-bound 48S initiation complex
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-22
公開日2020-10-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
7AAV
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BU of 7aav by Molmil
Human pre-Bact-2 spliceosome core structure
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-04
公開日2020-12-09
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
6ZVJ
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BU of 6zvj by Molmil
Structure of a human ABCE1-bound 43S pre-initiation complex - State II
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-24
公開日2020-10-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
6ZMW
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BU of 6zmw by Molmil
Structure of a human 48S translational initiation complex
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
登録日2020-07-04
公開日2020-09-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
7W5B
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BU of 7w5b by Molmil
The cryo-EM structure of human C* complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2021-11-29
公開日2022-06-22
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
7W5A
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BU of 7w5a by Molmil
The cryo-EM structure of human pre-C*-II complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2021-11-29
公開日2022-06-22
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
7W59
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BU of 7w59 by Molmil
The cryo-EM structure of human pre-C*-I complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2021-11-29
公開日2022-06-22
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
7QP7
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BU of 7qp7 by Molmil
Structure of the human 48S initiation complex in closed state (h48S AUG closed)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N.
登録日2022-01-03
公開日2022-05-11
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.
Nucleic Acids Res., 50, 2022
7QP6
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BU of 7qp6 by Molmil
Structure of the human 48S initiation complex in open state (h48S AUG open)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N.
登録日2022-01-03
公開日2022-05-11
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Conformational rearrangements upon start codon recognition in human 48S translation initiation complex.
Nucleic Acids Res., 50, 2022
7QTT
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BU of 7qtt by Molmil
Structural organization of a late activated human spliceosome (Baqr, core region)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
著者Cretu, C, Pena, V.
登録日2022-01-15
公開日2023-05-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
7A09
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BU of 7a09 by Molmil
Structure of a human ABCE1-bound 43S pre-initiation complex - State III
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-08-07
公開日2020-10-14
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
7ABI
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BU of 7abi by Molmil
Human pre-Bact-2 spliceosome
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-07
公開日2021-02-10
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7B9V
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BU of 7b9v by Molmil
Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound
分子名称: 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ...
著者Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K.
登録日2020-12-14
公開日2021-03-10
最終更新日2021-04-14
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for conformational equilibrium of the catalytic spliceosome.
Mol.Cell, 81, 2021
7ABG
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BU of 7abg by Molmil
Human pre-Bact-1 spliceosome
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-07
公開日2020-12-23
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
6ZP4
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BU of 6zp4 by Molmil
SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-08
公開日2020-07-29
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
7ASE
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BU of 7ase by Molmil
43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase
分子名称: 18S, 40S ribosomal protein S10, putative, ...
著者Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y.
登録日2020-10-27
公開日2021-04-14
最終更新日2021-04-21
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts.
Cell Rep, 33, 2020
5LJ3
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BU of 5lj3 by Molmil
Structure of the core of the yeast spliceosome immediately after branching
分子名称: CEF1, CLF1, CWC15, ...
著者Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K.
登録日2016-07-17
公開日2016-08-03
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
5MPS
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BU of 5mps by Molmil
Structure of a spliceosome remodeled for exon ligation
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K.
登録日2016-12-18
公開日2017-01-18
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5MQ0
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BU of 5mq0 by Molmil
Structure of a spliceosome remodeled for exon ligation
分子名称: 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ...
著者Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K.
登録日2016-12-19
公開日2017-01-18
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (4.17 Å)
主引用文献Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5LJ5
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BU of 5lj5 by Molmil
Overall structure of the yeast spliceosome immediately after branching.
分子名称: CWC15, CWC22, Exon 1 (5' exon) of UBC4 pre-mRNA, ...
著者Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K.
登録日2016-07-17
公開日2016-08-31
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
5LQW
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BU of 5lqw by Molmil
yeast activated spliceosome
分子名称: Pre-mRNA leakage protein 1, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor 8, ...
著者Rauhut, R, Luehrmann, R.
登録日2016-08-17
公開日2016-10-05
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
Science, 6306, 2016
5MQF
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BU of 5mqf by Molmil
Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ...
著者Bertram, K, Hartmuth, K, Kastner, B.
登録日2016-12-20
公開日2017-03-22
最終更新日2018-11-21
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature, 542, 2017
5NRL
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BU of 5nrl by Molmil
Structure of a pre-catalytic spliceosome.
分子名称: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ...
著者Plaschka, C, Lin, P.-C, Nagai, K.
登録日2017-04-24
公開日2017-05-31
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Structure of a pre-catalytic spliceosome.
Nature, 546, 2017
5XJC
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BU of 5xjc by Molmil
Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y.
登録日2017-04-30
公開日2017-07-05
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献An Atomic Structure of the Human Spliceosome
Cell, 169, 2017
5YLZ
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BU of 5ylz by Molmil
Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom
分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y.
登録日2017-10-20
公開日2018-07-18
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
Cell, 171, 2017

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