7QTT

Structural organization of a late activated human spliceosome (Baqr, core region)

Summary for 7QTT

• Entry DOI: 10.2210/pdb7qtt/pdb
• Related: 5Z57 6FF4
• EMDB information: 14146
• Descriptor: Splicing factor 3B subunit 3, BUD13 homolog, Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16, ... (41 entities in total)
• Functional Keywords: spliceosome, helicase, prp2, aquarius, catalytic activation, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 37
• Total formula weight: 2495692.23

Authors

Cretu, C.,Pena, V. (deposition date: 2022-01-15, release date: 2023-05-10, Last modification date: 2023-06-14)

• Primary citation: Schmitzova, J.,Cretu, C.,Dienemann, C.,Urlaub, H.,Pena, V.; Structural basis of catalytic activation in human splicing.; Nature, 617:842-850, 2023; PubMed: 37165190; DOI: 10.1038/s41586-023-06049-w

Experimental method

ELECTRON MICROSCOPY (3.1 Å)