7QTT

Structural organization of a late activated human spliceosome (Baqr, core region)

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000244	biological_process	spliceosomal tri-snRNP complex assembly
a	0000375	biological_process	RNA splicing, via transesterification reactions
a	0000398	biological_process	mRNA splicing, via spliceosome
a	0003723	molecular_function	RNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005681	cellular_component	spliceosomal complex
a	0005682	cellular_component	U5 snRNP
a	0006397	biological_process	mRNA processing
a	0008233	molecular_function	peptidase activity
a	0008237	molecular_function	metallopeptidase activity
a	0008380	biological_process	RNA splicing
a	0016020	cellular_component	membrane
a	0016607	cellular_component	nuclear speck
a	0017070	molecular_function	U6 snRNA binding
a	0030532	cellular_component	small nuclear ribonucleoprotein complex
a	0030619	molecular_function	U1 snRNA binding
a	0030620	molecular_function	U2 snRNA binding
a	0030623	molecular_function	U5 snRNA binding
a	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
a	0070530	molecular_function	K63-linked polyubiquitin modification-dependent protein binding
a	0071005	cellular_component	U2-type precatalytic spliceosome
a	0071006	cellular_component	U2-type catalytic step 1 spliceosome
a	0071007	cellular_component	U2-type catalytic step 2 spliceosome
a	0071013	cellular_component	catalytic step 2 spliceosome
a	0071222	biological_process	cellular response to lipopolysaccharide
a	0071356	biological_process	cellular response to tumor necrosis factor
a	0097157	molecular_function	pre-mRNA intronic binding
a	0140492	molecular_function	metal-dependent deubiquitinase activity
A	0000124	cellular_component	SAGA complex
A	0000375	biological_process	RNA splicing, via transesterification reactions
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003676	molecular_function	nucleic acid binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005684	cellular_component	U2-type spliceosomal complex
A	0005686	cellular_component	U2 snRNP
A	0005689	cellular_component	U12-type spliceosomal complex
A	0005730	cellular_component	nucleolus
A	0006282	biological_process	regulation of DNA repair
A	0006397	biological_process	mRNA processing
A	0008380	biological_process	RNA splicing
A	0030620	molecular_function	U2 snRNA binding
A	0042177	biological_process	negative regulation of protein catabolic process
A	0043484	biological_process	regulation of RNA splicing
A	0044877	molecular_function	protein-containing complex binding
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	1903241	biological_process	U2-type prespliceosome assembly
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003723	molecular_function	RNA binding
b	0003924	molecular_function	GTPase activity
b	0005515	molecular_function	protein binding
b	0005525	molecular_function	GTP binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005681	cellular_component	spliceosomal complex
b	0005829	cellular_component	cytosol
b	0006397	biological_process	mRNA processing
b	0008380	biological_process	RNA splicing
b	0015030	cellular_component	Cajal body
b	0016020	cellular_component	membrane
b	0016607	cellular_component	nuclear speck
b	0030623	molecular_function	U5 snRNA binding
b	0042220	biological_process	response to cocaine
b	0043231	cellular_component	intracellular membrane-bounded organelle
b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
b	0071005	cellular_component	U2-type precatalytic spliceosome
b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
b	0071013	cellular_component	catalytic step 2 spliceosome
b	0071466	biological_process	cellular response to xenobiotic stimulus
B	0000124	cellular_component	SAGA complex
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005684	cellular_component	U2-type spliceosomal complex
B	0005686	cellular_component	U2 snRNP
B	0005689	cellular_component	U12-type spliceosomal complex
B	0006282	biological_process	regulation of DNA repair
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0043484	biological_process	regulation of RNA splicing
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0071005	cellular_component	U2-type precatalytic spliceosome
B	0071011	cellular_component	precatalytic spliceosome
B	1903241	biological_process	U2-type prespliceosome assembly
B	1990935	molecular_function	splicing factor binding
C	0000245	biological_process	spliceosomal complex assembly
C	0000375	biological_process	RNA splicing, via transesterification reactions
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003723	molecular_function	RNA binding
C	0003729	molecular_function	mRNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0005684	cellular_component	U2-type spliceosomal complex
C	0005686	cellular_component	U2 snRNP
C	0005689	cellular_component	U12-type spliceosomal complex
C	0005730	cellular_component	nucleolus
C	0006338	biological_process	chromatin remodeling
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0016607	cellular_component	nuclear speck
C	0034693	cellular_component	U11/U12 snRNP
C	0045943	biological_process	positive regulation of transcription by RNA polymerase I
C	0045944	biological_process	positive regulation of transcription by RNA polymerase II
C	0045945	biological_process	positive regulation of transcription by RNA polymerase III
C	0071004	cellular_component	U2-type prespliceosome
C	0071005	cellular_component	U2-type precatalytic spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	0110016	cellular_component	B-WICH complex
C	1903241	biological_process	U2-type prespliceosome assembly
C	1990935	molecular_function	splicing factor binding
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0003677	molecular_function	DNA binding
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0005684	cellular_component	U2-type spliceosomal complex
D	0005686	cellular_component	U2 snRNP
D	0005689	cellular_component	U12-type spliceosomal complex
D	0006397	biological_process	mRNA processing
D	0008270	molecular_function	zinc ion binding
D	0008380	biological_process	RNA splicing
D	0016363	cellular_component	nuclear matrix
D	0016607	cellular_component	nuclear speck
D	0045893	biological_process	positive regulation of DNA-templated transcription
D	0046872	molecular_function	metal ion binding
D	0048863	biological_process	stem cell differentiation
D	0071005	cellular_component	U2-type precatalytic spliceosome
D	0071011	cellular_component	precatalytic spliceosome
D	1903241	biological_process	U2-type prespliceosome assembly
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005684	cellular_component	U2-type spliceosomal complex
E	0005686	cellular_component	U2 snRNP
E	0005689	cellular_component	U12-type spliceosomal complex
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0016607	cellular_component	nuclear speck
E	0071005	cellular_component	U2-type precatalytic spliceosome
E	0071011	cellular_component	precatalytic spliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
E	1903241	biological_process	U2-type prespliceosome assembly
F	0000375	biological_process	RNA splicing, via transesterification reactions
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0003676	molecular_function	nucleic acid binding
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005681	cellular_component	spliceosomal complex
F	0005684	cellular_component	U2-type spliceosomal complex
F	0005686	cellular_component	U2 snRNP
F	0005689	cellular_component	U12-type spliceosomal complex
F	0006397	biological_process	mRNA processing
F	0008380	biological_process	RNA splicing
F	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
F	0071005	cellular_component	U2-type precatalytic spliceosome
F	1903241	biological_process	U2-type prespliceosome assembly
F	1990935	molecular_function	splicing factor binding
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0003676	molecular_function	nucleic acid binding
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005681	cellular_component	spliceosomal complex
G	0006397	biological_process	mRNA processing
G	0008380	biological_process	RNA splicing
h	0000387	biological_process	spliceosomal snRNP assembly
h	0000398	biological_process	mRNA splicing, via spliceosome
h	0003723	molecular_function	RNA binding
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005681	cellular_component	spliceosomal complex
h	0005682	cellular_component	U5 snRNP
h	0005683	cellular_component	U7 snRNP
h	0005684	cellular_component	U2-type spliceosomal complex
h	0005685	cellular_component	U1 snRNP
h	0005686	cellular_component	U2 snRNP
h	0005687	cellular_component	U4 snRNP
h	0005689	cellular_component	U12-type spliceosomal complex
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0006397	biological_process	mRNA processing
h	0008380	biological_process	RNA splicing
h	0030532	cellular_component	small nuclear ribonucleoprotein complex
h	0034709	cellular_component	methylosome
h	0034715	cellular_component	pICln-Sm protein complex
h	0034719	cellular_component	SMN-Sm protein complex
h	0036261	biological_process	7-methylguanosine cap hypermethylation
h	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
h	0071005	cellular_component	U2-type precatalytic spliceosome
h	0071007	cellular_component	U2-type catalytic step 2 spliceosome
h	0071013	cellular_component	catalytic step 2 spliceosome
h	0120114	cellular_component	Sm-like protein family complex
h	1903241	biological_process	U2-type prespliceosome assembly
i	0000245	biological_process	spliceosomal complex assembly
i	0000387	biological_process	spliceosomal snRNP assembly
i	0000398	biological_process	mRNA splicing, via spliceosome
i	0003723	molecular_function	RNA binding
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005681	cellular_component	spliceosomal complex
i	0005682	cellular_component	U5 snRNP
i	0005683	cellular_component	U7 snRNP
i	0005684	cellular_component	U2-type spliceosomal complex
i	0005685	cellular_component	U1 snRNP
i	0005686	cellular_component	U2 snRNP
i	0005687	cellular_component	U4 snRNP
i	0005689	cellular_component	U12-type spliceosomal complex
i	0005697	cellular_component	telomerase holoenzyme complex
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0006397	biological_process	mRNA processing
i	0008380	biological_process	RNA splicing
i	0030532	cellular_component	small nuclear ribonucleoprotein complex
i	0034709	cellular_component	methylosome
i	0034715	cellular_component	pICln-Sm protein complex
i	0034719	cellular_component	SMN-Sm protein complex
i	0036261	biological_process	7-methylguanosine cap hypermethylation
i	0043229	cellular_component	intracellular organelle
i	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
i	0071005	cellular_component	U2-type precatalytic spliceosome
i	0071007	cellular_component	U2-type catalytic step 2 spliceosome
i	0071011	cellular_component	precatalytic spliceosome
i	0071013	cellular_component	catalytic step 2 spliceosome
i	1903241	biological_process	U2-type prespliceosome assembly
I	0000245	biological_process	spliceosomal complex assembly
I	0000389	biological_process	mRNA 3'-splice site recognition
I	0000398	biological_process	mRNA splicing, via spliceosome
I	0003676	molecular_function	nucleic acid binding
I	0003723	molecular_function	RNA binding
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005681	cellular_component	spliceosomal complex
I	0005684	cellular_component	U2-type spliceosomal complex
I	0005686	cellular_component	U2 snRNP
I	0006397	biological_process	mRNA processing
I	0008270	molecular_function	zinc ion binding
I	0008380	biological_process	RNA splicing
I	0010976	biological_process	positive regulation of neuron projection development
I	0016607	cellular_component	nuclear speck
I	0046872	molecular_function	metal ion binding
I	0071004	cellular_component	U2-type prespliceosome
I	0071005	cellular_component	U2-type precatalytic spliceosome
I	0071013	cellular_component	catalytic step 2 spliceosome
I	1903241	biological_process	U2-type prespliceosome assembly
j	0000243	cellular_component	commitment complex
j	0000387	biological_process	spliceosomal snRNP assembly
j	0000398	biological_process	mRNA splicing, via spliceosome
j	0003723	molecular_function	RNA binding
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005681	cellular_component	spliceosomal complex
j	0005682	cellular_component	U5 snRNP
j	0005683	cellular_component	U7 snRNP
j	0005684	cellular_component	U2-type spliceosomal complex
j	0005685	cellular_component	U1 snRNP
j	0005686	cellular_component	U2 snRNP
j	0005687	cellular_component	U4 snRNP
j	0005689	cellular_component	U12-type spliceosomal complex
j	0005697	cellular_component	telomerase holoenzyme complex
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0006396	biological_process	RNA processing
j	0006397	biological_process	mRNA processing
j	0006479	biological_process	protein methylation
j	0008380	biological_process	RNA splicing
j	0016604	cellular_component	nuclear body
j	0019899	molecular_function	enzyme binding
j	0030532	cellular_component	small nuclear ribonucleoprotein complex
j	0034709	cellular_component	methylosome
j	0034715	cellular_component	pICln-Sm protein complex
j	0034719	cellular_component	SMN-Sm protein complex
j	0036261	biological_process	7-methylguanosine cap hypermethylation
j	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
j	0070034	molecular_function	telomerase RNA binding
j	0071005	cellular_component	U2-type precatalytic spliceosome
j	0071007	cellular_component	U2-type catalytic step 2 spliceosome
j	0071011	cellular_component	precatalytic spliceosome
j	0071013	cellular_component	catalytic step 2 spliceosome
j	0071208	molecular_function	histone pre-mRNA DCP binding
j	0071209	molecular_function	U7 snRNA binding
j	0097526	cellular_component	spliceosomal tri-snRNP complex
j	1903241	biological_process	U2-type prespliceosome assembly
j	1990446	molecular_function	U1 snRNP binding
J	0000375	biological_process	RNA splicing, via transesterification reactions
J	0000389	biological_process	mRNA 3'-splice site recognition
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0003676	molecular_function	nucleic acid binding
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005681	cellular_component	spliceosomal complex
J	0005684	cellular_component	U2-type spliceosomal complex
J	0005686	cellular_component	U2 snRNP
J	0006397	biological_process	mRNA processing
J	0008270	molecular_function	zinc ion binding
J	0008380	biological_process	RNA splicing
J	0016607	cellular_component	nuclear speck
J	0046872	molecular_function	metal ion binding
J	0071005	cellular_component	U2-type precatalytic spliceosome
J	0071013	cellular_component	catalytic step 2 spliceosome
J	1903241	biological_process	U2-type prespliceosome assembly
k	0000243	cellular_component	commitment complex
k	0000245	biological_process	spliceosomal complex assembly
k	0000387	biological_process	spliceosomal snRNP assembly
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005681	cellular_component	spliceosomal complex
k	0005682	cellular_component	U5 snRNP
k	0005684	cellular_component	U2-type spliceosomal complex
k	0005685	cellular_component	U1 snRNP
k	0005686	cellular_component	U2 snRNP
k	0005687	cellular_component	U4 snRNP
k	0005689	cellular_component	U12-type spliceosomal complex
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0006396	biological_process	RNA processing
k	0006397	biological_process	mRNA processing
k	0008380	biological_process	RNA splicing
k	0030532	cellular_component	small nuclear ribonucleoprotein complex
k	0034709	cellular_component	methylosome
k	0034715	cellular_component	pICln-Sm protein complex
k	0034719	cellular_component	SMN-Sm protein complex
k	0036261	biological_process	7-methylguanosine cap hypermethylation
k	0043229	cellular_component	intracellular organelle
k	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
k	0071005	cellular_component	U2-type precatalytic spliceosome
k	0071007	cellular_component	U2-type catalytic step 2 spliceosome
k	0071011	cellular_component	precatalytic spliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	0097526	cellular_component	spliceosomal tri-snRNP complex
k	1903241	biological_process	U2-type prespliceosome assembly
l	0000245	biological_process	spliceosomal complex assembly
l	0000387	biological_process	spliceosomal snRNP assembly
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003723	molecular_function	RNA binding
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005681	cellular_component	spliceosomal complex
l	0005682	cellular_component	U5 snRNP
l	0005684	cellular_component	U2-type spliceosomal complex
l	0005685	cellular_component	U1 snRNP
l	0005686	cellular_component	U2 snRNP
l	0005687	cellular_component	U4 snRNP
l	0005689	cellular_component	U12-type spliceosomal complex
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006397	biological_process	mRNA processing
l	0008380	biological_process	RNA splicing
l	0030532	cellular_component	small nuclear ribonucleoprotein complex
l	0034709	cellular_component	methylosome
l	0034715	cellular_component	pICln-Sm protein complex
l	0034719	cellular_component	SMN-Sm protein complex
l	0036261	biological_process	7-methylguanosine cap hypermethylation
l	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
l	0070062	cellular_component	extracellular exosome
l	0071005	cellular_component	U2-type precatalytic spliceosome
l	0071007	cellular_component	U2-type catalytic step 2 spliceosome
l	0071011	cellular_component	precatalytic spliceosome
l	0071013	cellular_component	catalytic step 2 spliceosome
l	1903241	biological_process	U2-type prespliceosome assembly
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005681	cellular_component	spliceosomal complex
L	0005684	cellular_component	U2-type spliceosomal complex
L	0005686	cellular_component	U2 snRNP
L	0006397	biological_process	mRNA processing
L	0008380	biological_process	RNA splicing
L	0070274	cellular_component	RES complex
L	0071005	cellular_component	U2-type precatalytic spliceosome
L	1903241	biological_process	U2-type prespliceosome assembly
m	0000245	biological_process	spliceosomal complex assembly
m	0000387	biological_process	spliceosomal snRNP assembly
m	0000398	biological_process	mRNA splicing, via spliceosome
m	0003723	molecular_function	RNA binding
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005654	cellular_component	nucleoplasm
m	0005681	cellular_component	spliceosomal complex
m	0005682	cellular_component	U5 snRNP
m	0005683	cellular_component	U7 snRNP
m	0005684	cellular_component	U2-type spliceosomal complex
m	0005685	cellular_component	U1 snRNP
m	0005686	cellular_component	U2 snRNP
m	0005687	cellular_component	U4 snRNP
m	0005689	cellular_component	U12-type spliceosomal complex
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0006397	biological_process	mRNA processing
m	0008380	biological_process	RNA splicing
m	0030532	cellular_component	small nuclear ribonucleoprotein complex
m	0034709	cellular_component	methylosome
m	0034719	cellular_component	SMN-Sm protein complex
m	0036261	biological_process	7-methylguanosine cap hypermethylation
m	0043186	cellular_component	P granule
m	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
m	0071004	cellular_component	U2-type prespliceosome
m	0071005	cellular_component	U2-type precatalytic spliceosome
m	0071007	cellular_component	U2-type catalytic step 2 spliceosome
m	0071011	cellular_component	precatalytic spliceosome
m	0071013	cellular_component	catalytic step 2 spliceosome
m	0097526	cellular_component	spliceosomal tri-snRNP complex
m	1903241	biological_process	U2-type prespliceosome assembly
n	0000387	biological_process	spliceosomal snRNP assembly
n	0000398	biological_process	mRNA splicing, via spliceosome
n	0003723	molecular_function	RNA binding
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0005681	cellular_component	spliceosomal complex
n	0005682	cellular_component	U5 snRNP
n	0005683	cellular_component	U7 snRNP
n	0005684	cellular_component	U2-type spliceosomal complex
n	0005685	cellular_component	U1 snRNP
n	0005686	cellular_component	U2 snRNP
n	0005687	cellular_component	U4 snRNP
n	0005689	cellular_component	U12-type spliceosomal complex
n	0005697	cellular_component	telomerase holoenzyme complex
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006397	biological_process	mRNA processing
n	0006479	biological_process	protein methylation
n	0008380	biological_process	RNA splicing
n	0030532	cellular_component	small nuclear ribonucleoprotein complex
n	0034709	cellular_component	methylosome
n	0034719	cellular_component	SMN-Sm protein complex
n	0036261	biological_process	7-methylguanosine cap hypermethylation
n	0043229	cellular_component	intracellular organelle
n	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
n	0070034	molecular_function	telomerase RNA binding
n	0070990	molecular_function	snRNP binding
n	0071004	cellular_component	U2-type prespliceosome
n	0071005	cellular_component	U2-type precatalytic spliceosome
n	0071007	cellular_component	U2-type catalytic step 2 spliceosome
n	0071013	cellular_component	catalytic step 2 spliceosome
n	0071204	cellular_component	histone pre-mRNA 3'end processing complex
n	0071208	molecular_function	histone pre-mRNA DCP binding
n	1903241	biological_process	U2-type prespliceosome assembly
n	1990446	molecular_function	U1 snRNP binding
n	1990447	molecular_function	U2 snRNP binding
N	0000398	biological_process	mRNA splicing, via spliceosome
N	0003676	molecular_function	nucleic acid binding
N	0003723	molecular_function	RNA binding
N	0003724	molecular_function	RNA helicase activity
N	0004386	molecular_function	helicase activity
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005681	cellular_component	spliceosomal complex
N	0005737	cellular_component	cytoplasm
N	0006397	biological_process	mRNA processing
N	0008380	biological_process	RNA splicing
N	0016787	molecular_function	hydrolase activity
N	0016887	molecular_function	ATP hydrolysis activity
N	0038187	molecular_function	pattern recognition receptor activity
N	0043130	molecular_function	ubiquitin binding
N	0045087	biological_process	innate immune response
N	0060090	molecular_function	molecular adaptor activity
N	0071005	cellular_component	U2-type precatalytic spliceosome
N	0140374	biological_process	antiviral innate immune response
O	0000398	biological_process	mRNA splicing, via spliceosome
O	0000974	cellular_component	Prp19 complex
O	0001650	cellular_component	fibrillar center
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005662	cellular_component	DNA replication factor A complex
O	0005681	cellular_component	spliceosomal complex
O	0006397	biological_process	mRNA processing
O	0008380	biological_process	RNA splicing
O	0016607	cellular_component	nuclear speck
O	0031965	cellular_component	nuclear membrane
O	0034504	biological_process	protein localization to nucleus
O	0071007	cellular_component	U2-type catalytic step 2 spliceosome
O	0071013	cellular_component	catalytic step 2 spliceosome
O	1900087	biological_process	positive regulation of G1/S transition of mitotic cell cycle
p	0000398	biological_process	mRNA splicing, via spliceosome
p	0000413	biological_process	protein peptidyl-prolyl isomerization
p	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005654	cellular_component	nucleoplasm
p	0005681	cellular_component	spliceosomal complex
p	0006397	biological_process	mRNA processing
p	0006457	biological_process	protein folding
p	0008380	biological_process	RNA splicing
p	0016018	molecular_function	cyclosporin A binding
p	0071007	cellular_component	U2-type catalytic step 2 spliceosome
p	0071013	cellular_component	catalytic step 2 spliceosome
p	0097718	molecular_function	disordered domain specific binding
p	1990403	biological_process	embryonic brain development
P	0000077	biological_process	DNA damage checkpoint signaling
P	0000398	biological_process	mRNA splicing, via spliceosome
P	0000974	cellular_component	Prp19 complex
P	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
P	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
P	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
P	0003677	molecular_function	DNA binding
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005662	cellular_component	DNA replication factor A complex
P	0005681	cellular_component	spliceosomal complex
P	0005737	cellular_component	cytoplasm
P	0006281	biological_process	DNA repair
P	0006357	biological_process	regulation of transcription by RNA polymerase II
P	0006397	biological_process	mRNA processing
P	0008380	biological_process	RNA splicing
P	0016020	cellular_component	membrane
P	0016607	cellular_component	nuclear speck
P	0042802	molecular_function	identical protein binding
P	0045944	biological_process	positive regulation of transcription by RNA polymerase II
P	0071007	cellular_component	U2-type catalytic step 2 spliceosome
P	0071013	cellular_component	catalytic step 2 spliceosome
P	0071987	molecular_function	WD40-repeat domain binding
q	0000398	biological_process	mRNA splicing, via spliceosome
q	0003723	molecular_function	RNA binding
q	0003729	molecular_function	mRNA binding
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005681	cellular_component	spliceosomal complex
q	0006397	biological_process	mRNA processing
q	0008380	biological_process	RNA splicing
q	0015030	cellular_component	Cajal body
q	0016607	cellular_component	nuclear speck
q	0070742	molecular_function	C2H2 zinc finger domain binding
q	0071005	cellular_component	U2-type precatalytic spliceosome
q	0071007	cellular_component	U2-type catalytic step 2 spliceosome
q	0071013	cellular_component	catalytic step 2 spliceosome
Q	0000398	biological_process	mRNA splicing, via spliceosome
Q	0000974	cellular_component	Prp19 complex
Q	0003723	molecular_function	RNA binding
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005681	cellular_component	spliceosomal complex
Q	0005739	cellular_component	mitochondrion
Q	0006397	biological_process	mRNA processing
Q	0008380	biological_process	RNA splicing
Q	0016607	cellular_component	nuclear speck
Q	0045292	biological_process	mRNA cis splicing, via spliceosome
Q	0071007	cellular_component	U2-type catalytic step 2 spliceosome
Q	0071013	cellular_component	catalytic step 2 spliceosome
T	0000398	biological_process	mRNA splicing, via spliceosome
T	0000785	cellular_component	chromatin
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005681	cellular_component	spliceosomal complex
T	0006397	biological_process	mRNA processing
T	0008380	biological_process	RNA splicing
T	0016922	molecular_function	nuclear receptor binding
T	0030374	molecular_function	nuclear receptor coactivator activity
T	0045893	biological_process	positive regulation of DNA-templated transcription
T	0071007	cellular_component	U2-type catalytic step 2 spliceosome
T	2000825	biological_process	positive regulation of androgen receptor activity
u	0000209	biological_process	protein polyubiquitination
u	0000413	biological_process	protein peptidyl-prolyl isomerization
u	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
u	0004842	molecular_function	ubiquitin-protein transferase activity
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005654	cellular_component	nucleoplasm
u	0005681	cellular_component	spliceosomal complex
u	0005737	cellular_component	cytoplasm
u	0005796	cellular_component	Golgi lumen
u	0005886	cellular_component	plasma membrane
u	0006397	biological_process	mRNA processing
u	0006457	biological_process	protein folding
u	0008380	biological_process	RNA splicing
u	0016018	molecular_function	cyclosporin A binding
u	0016567	biological_process	protein ubiquitination
u	0016740	molecular_function	transferase activity
u	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
u	0061630	molecular_function	ubiquitin protein ligase activity
u	0071013	cellular_component	catalytic step 2 spliceosome
u	0072659	biological_process	protein localization to plasma membrane
U	0000398	biological_process	mRNA splicing, via spliceosome
U	0000974	cellular_component	Prp19 complex
U	0003676	molecular_function	nucleic acid binding
U	0003723	molecular_function	RNA binding
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005681	cellular_component	spliceosomal complex
U	0005737	cellular_component	cytoplasm
U	0006397	biological_process	mRNA processing
U	0008380	biological_process	RNA splicing
U	0017070	molecular_function	U6 snRNA binding
U	0033120	biological_process	positive regulation of RNA splicing
U	0036002	molecular_function	pre-mRNA binding
U	0042307	biological_process	positive regulation of protein import into nucleus
U	0045292	biological_process	mRNA cis splicing, via spliceosome
U	0046827	biological_process	positive regulation of protein export from nucleus
U	0046872	molecular_function	metal ion binding
U	0048306	molecular_function	calcium-dependent protein binding
U	0071006	cellular_component	U2-type catalytic step 1 spliceosome
U	0071007	cellular_component	U2-type catalytic step 2 spliceosome
U	0071013	cellular_component	catalytic step 2 spliceosome
U	0071466	biological_process	cellular response to xenobiotic stimulus
V	0000413	biological_process	protein peptidyl-prolyl isomerization
V	0003676	molecular_function	nucleic acid binding
V	0003723	molecular_function	RNA binding
V	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005829	cellular_component	cytosol
W	0000398	biological_process	mRNA splicing, via spliceosome
W	0003723	molecular_function	RNA binding
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005681	cellular_component	spliceosomal complex
W	0005829	cellular_component	cytosol
W	0006397	biological_process	mRNA processing
W	0008380	biological_process	RNA splicing
W	0016607	cellular_component	nuclear speck
W	0048024	biological_process	regulation of mRNA splicing, via spliceosome
W	0071005	cellular_component	U2-type precatalytic spliceosome
W	0071006	cellular_component	U2-type catalytic step 1 spliceosome
W	0071007	cellular_component	U2-type catalytic step 2 spliceosome
W	0071013	cellular_component	catalytic step 2 spliceosome
X	0000245	biological_process	spliceosomal complex assembly
X	0000398	biological_process	mRNA splicing, via spliceosome
X	0000974	cellular_component	Prp19 complex
X	0003723	molecular_function	RNA binding
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005681	cellular_component	spliceosomal complex
X	0006396	biological_process	RNA processing
X	0006397	biological_process	mRNA processing
X	0008380	biological_process	RNA splicing
X	0016607	cellular_component	nuclear speck
X	0071007	cellular_component	U2-type catalytic step 2 spliceosome
X	0071013	cellular_component	catalytic step 2 spliceosome
X	0071014	cellular_component	post-mRNA release spliceosomal complex
Y	0000122	biological_process	negative regulation of transcription by RNA polymerase II
Y	0000398	biological_process	mRNA splicing, via spliceosome
Y	0003713	molecular_function	transcription coactivator activity
Y	0003714	molecular_function	transcription corepressor activity
Y	0003723	molecular_function	RNA binding
Y	0005112	molecular_function	Notch binding
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005681	cellular_component	spliceosomal complex
Y	0006357	biological_process	regulation of transcription by RNA polymerase II
Y	0006397	biological_process	mRNA processing
Y	0008024	cellular_component	cyclin/CDK positive transcription elongation factor complex
Y	0008380	biological_process	RNA splicing
Y	0016363	cellular_component	nuclear matrix
Y	0016604	cellular_component	nuclear body
Y	0016607	cellular_component	nuclear speck
Y	0016922	molecular_function	nuclear receptor binding
Y	0019899	molecular_function	enzyme binding
Y	0030511	biological_process	positive regulation of transforming growth factor beta receptor signaling pathway
Y	0042771	biological_process	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Y	0042809	molecular_function	nuclear vitamin D receptor binding
Y	0042974	molecular_function	nuclear retinoic acid receptor binding
Y	0043923	biological_process	positive regulation by host of viral transcription
Y	0045892	biological_process	negative regulation of DNA-templated transcription
Y	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Y	0046332	molecular_function	SMAD binding
Y	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
Y	0048384	biological_process	retinoic acid receptor signaling pathway
Y	0048385	biological_process	regulation of retinoic acid receptor signaling pathway
Y	0050681	molecular_function	nuclear androgen receptor binding
Y	0050769	biological_process	positive regulation of neurogenesis
Y	0070562	biological_process	regulation of vitamin D receptor signaling pathway
Y	0070564	biological_process	positive regulation of vitamin D receptor signaling pathway
Y	0071007	cellular_component	U2-type catalytic step 2 spliceosome
Y	0071013	cellular_component	catalytic step 2 spliceosome
Y	0071300	biological_process	cellular response to retinoic acid
Z	0000398	biological_process	mRNA splicing, via spliceosome
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005681	cellular_component	spliceosomal complex
Z	0005684	cellular_component	U2-type spliceosomal complex
Z	0006281	biological_process	DNA repair
Z	0006397	biological_process	mRNA processing
Z	0008380	biological_process	RNA splicing
Z	0016567	biological_process	protein ubiquitination
Z	0016607	cellular_component	nuclear speck
Z	0016740	molecular_function	transferase activity
Z	0034247	biological_process	snoRNA splicing
Z	0046872	molecular_function	metal ion binding
Z	0061630	molecular_function	ubiquitin protein ligase activity
Z	0070100	biological_process	negative regulation of chemokine-mediated signaling pathway
Z	0071005	cellular_component	U2-type precatalytic spliceosome

Functional Information from PROSITE/UniProt

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YdgTiFHRSIrnFViQGG

Chain	Residue	Details
u	TYR316-GLY333
p	TYR48-GLY65

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FVCSATH

Chain	Residue	Details
A	PHE287-HIS293

---

site_id	PS00518
Number of Residues	10
Details	ZF_RING_1 Zinc finger RING-type signature. CrHyFCesCA

Chain	Residue	Details
Z	CYS277-ALA286

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVTCsrDsTARIWDV

Chain	Residue	Details
O	LEU303-VAL317
O	ILE345-LEU359

---

site_id	PS00690
Number of Residues	10
Details	DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. SvVMVDEAHE

Chain	Residue	Details
N	SER515-GLU524

---

site_id	PS00997
Number of Residues	23
Details	G10_1 G10 protein signature 1. LCClRCiqtrDtNfgtnCiCRVP

Chain	Residue	Details
T	LEU100-PRO122

---

site_id	PS00998
Number of Residues	10
Details	G10_2 G10 protein signature 2. CtHCGCRGCS

Chain	Residue	Details
T	CYS134-SER143

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
u	SER470
D	CYS72
D	CYS75
D	CYS85
p	THR70
p	ALA99
p	GLY109
p	THR119
p	LYS125
L	SER407
L	SER567
D	CYS61

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
u	LYS482
Y	SER182
Y	SER190
Y	SER446
Y	SER479
Y	SER481

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
u	LYS216
U	SER102
J	SER295

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
q	LYS169
C	THR235
l	LYS8

---

site_id	SWS_FT_FI5
Number of Residues	19
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
q	SER220
q	SER1460
q	SER1462
q	SER1482
q	SER1483
q	SER1501
q	SER1621
q	SER1893
q	SER2343
q	SER2394
q	SER2453
q	SER222
q	SER454
q	SER484
q	SER486
q	SER875
q	SER1336
q	SER1368
q	SER1421

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
q	THR286
Y	LYS416
Y	LYS441
Y	LYS452
q	THR1892
Y	LYS122
Y	LYS141
Y	LYS158
Y	LYS262
Y	LYS290
Y	LYS340
Y	LYS340

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER295
q	SER994
q	SER1014

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER297
q	SER1179
q	SER2581

---

site_id	SWS_FT_FI9
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER300
q	SER1083
q	SER1152

---

site_id	SWS_FT_FI10
Number of Residues	6
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER322
q	SER857
q	SER952
q	SER1318
q	SER1401
q	SER2100

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER323
L	SER240
L	SER248

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER351
q	SER353
E	LYS280
E	LYS492
E	LYS543
E	LYS770
E	LYS790
E	LYS843
E	LYS857

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
q	SER357
q	SER358
q	SER846
q	SER1214

---

site_id	SWS_FT_FI14
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
q	THR359
q	THR1106
q	THR2381

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR367
P	LYS487

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER377

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	THR383
q	THR384

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER387

---

site_id	SWS_FT_FI19
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER395
q	SER935
q	SER1311
C	THR303
C	THR313

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER398

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER404
q	SER408

---

site_id	SWS_FT_FI22
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER424
q	SER1124
q	SER2702

---

site_id	SWS_FT_FI23
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER435
q	SER2121
q	SER2675
q	SER2677
q	SER780
q	SER864
q	SER1064
q	SER1112
q	SER1537
q	SER1539
q	SER1541
q	SER1876

---

site_id	SWS_FT_FI24
Number of Residues	24
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER436
q	SER704
q	SER706
q	SER992
q	SER1198
q	SER1227
q	SER1254
q	SER1257
q	SER1258
q	SER2018
q	SER2030
q	SER437
q	SER2042
q	SER2310
q	SER2368
q	SER2376
q	SER2740
q	SER506
q	SER508
q	SER510
q	SER534
q	SER536
q	SER543
q	SER702

---

site_id	SWS_FT_FI25
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER440
q	SER1188

---

site_id	SWS_FT_FI26
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER778
q	SER2123
q	SER2398
q	SER2407
q	SER2692

---

site_id	SWS_FT_FI27
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692

Chain	Residue	Details
q	SER783
q	SER1522
q	SER1970

---

site_id	SWS_FT_FI28
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8BTI8

Chain	Residue	Details
q	SER854
q	SER1423
q	SER1616
q	SER1620
q	SER1024
q	SER1042
q	SER1266
q	SER1270
q	SER1271
q	SER1348
q	SER1383
q	SER1384

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q8BTI8

Chain	Residue	Details
q	THR856

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	THR866

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:20068231

Chain	Residue	Details
q	SER871

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER876
C	THR436

---

site_id	SWS_FT_FI33
Number of Residues	24
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
q	SER908
q	SER1582
q	SER1598
q	SER1600
q	SER1601
q	SER1658
q	SER1727
q	SER1729
q	SER1731
q	SER1732
q	SER1818
q	SER1129
q	SER1822
q	SER1884
q	SER2090
q	SER2415
q	SER2429
q	SER1424
q	SER1517
q	SER1519
q	SER1521
q	SER1577
q	SER1579
q	SER1581

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER950

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER954

---

site_id	SWS_FT_FI36
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
q	SER957
q	SER1946
q	SER1958
q	SER2118
q	SER968
q	SER970
q	SER972
q	SER1032
q	SER1451
q	SER1691
q	SER1693
q	SER1923

---

site_id	SWS_FT_FI37
Number of Residues	18
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
q	SER973
q	SER1975
q	SER1984
q	SER1987
q	SER1996
q	SER1999
q	SER2008
q	SER2011
q	SER2664
q	SER2706
q	SER1497
q	SER1502
q	SER1762
q	SER1764
q	SER1890
q	SER1916
q	SER1919
q	SER1972

---

site_id	SWS_FT_FI38
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
q	SER974
q	SER1415
q	SER1925
q	SER1948
q	SER1960

---

site_id	SWS_FT_FI39
Number of Residues	7
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
q	THR977
q	THR1043
q	THR1931
q	THR1954
q	THR1966
q	THR1978
q	THR2092

---

site_id	SWS_FT_FI40
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	THR983

---

site_id	SWS_FT_FI41
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	TYR996
q	TYR1049

---

site_id	SWS_FT_FI42
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	THR1003

---

site_id	SWS_FT_FI43
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER1010

---

site_id	SWS_FT_FI44
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
q	SER1028
q	SER2690

---

site_id	SWS_FT_FI45
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER1069
q	SER1444
q	SER1542
q	SER1552
q	SER1694
q	SER1878
q	SER2412

---

site_id	SWS_FT_FI46
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648

Chain	Residue	Details
q	SER1072
q	SER1073

---

site_id	SWS_FT_FI47
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
q	SER1099
q	SER1101

---

site_id	SWS_FT_FI48
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332

Chain	Residue	Details
q	SER1102

---

site_id	SWS_FT_FI49
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER1103
q	SER1404
q	SER2132

---

site_id	SWS_FT_FI50
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER1122
q	SER1857
q	SER2335

---

site_id	SWS_FT_FI51
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER1132

---

site_id	SWS_FT_FI52
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR1208
q	THR1880

---

site_id	SWS_FT_FI53
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER1219

---

site_id	SWS_FT_FI54
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER1320
q	SER1387

---

site_id	SWS_FT_FI55
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER1326

---

site_id	SWS_FT_FI56
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER1329

---

site_id	SWS_FT_FI57
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER1382

---

site_id	SWS_FT_FI58
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER1403

---

site_id	SWS_FT_FI59
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR1413

---

site_id	SWS_FT_FI60
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR1434

---

site_id	SWS_FT_FI61
Number of Residues	5
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
q	THR1453
q	THR1472
q	THR1511
q	THR1698
q	THR2144

---

site_id	SWS_FT_FI62
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER1458
q	SER1648
q	SER2020
q	SER2032
q	SER2067

---

site_id	SWS_FT_FI63
Number of Residues	9
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER1463
q	SER1499
q	SER1854
q	SER2044
q	SER2046
q	SER2071
q	SER2426
q	SER2684
q	SER2688

---

site_id	SWS_FT_FI64
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR1492

---

site_id	SWS_FT_FI65
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17924679, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR1531

---

site_id	SWS_FT_FI66
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
q	THR1927
q	THR1950
q	THR1962

---

site_id	SWS_FT_FI67
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR2022
q	THR2034

---

site_id	SWS_FT_FI68
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR2069

---

site_id	SWS_FT_FI69
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER2102

---

site_id	SWS_FT_FI70
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR2104

---

site_id	SWS_FT_FI71
Number of Residues	7
Details	MOD_RES: Omega-N-methylarginine => ECO:0007744|PubMed:24129315

Chain	Residue	Details
q	ARG2194
q	ARG2207
q	ARG2231
q	ARG2246
q	ARG2274
q	ARG2288
q	ARG2342

---

site_id	SWS_FT_FI72
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER2272

---

site_id	SWS_FT_FI73
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR2289

---

site_id	SWS_FT_FI74
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243

Chain	Residue	Details
q	THR2291

---

site_id	SWS_FT_FI75
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
q	THR2302

---

site_id	SWS_FT_FI76
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR2316

---

site_id	SWS_FT_FI77
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR2329
q	THR2409

---

site_id	SWS_FT_FI78
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	SER2382

---

site_id	SWS_FT_FI79
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine; alternate => ECO:0007744|PubMed:24129315

Chain	Residue	Details
q	ARG2384

---

site_id	SWS_FT_FI80
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER2449

---

site_id	SWS_FT_FI81
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569

Chain	Residue	Details
q	THR2583

---

site_id	SWS_FT_FI82
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	THR2599
q	THR2738

---

site_id	SWS_FT_FI83
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
q	SER2694

---

site_id	SWS_FT_FI84
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
q	LYS108
q	LYS130
q	LYS2587

---