5XJC

Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom

This is a non-PDB format compatible entry.

Summary for 5XJC

• Entry DOI: 10.2210/pdb5xjc/pdb
• EMDB information: 6721
• Descriptor: Pre-mRNA-processing-splicing factor 8, Crooked neck-like protein 1, Pre-mRNA-splicing factor SPF27, ... (46 entities in total)
• Functional Keywords: rna splicing, human spliceosome, c* complex, atomic structure, step 2 factors, ejc, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 50
• Total formula weight: 2962080.49

Authors

Zhang, X.,Yan, C.,Hang, J.,Finci, I.L.,Lei, J.,Shi, Y. (deposition date: 2017-04-30, release date: 2017-07-05, Last modification date: 2020-10-14)

• Primary citation: Zhang, X.,Yan, C.,Hang, J.,Finci, L.I.,Lei, J.,Shi, Y.; An Atomic Structure of the Human Spliceosome; Cell, 169:918-929.e14, 2017; PubMed: 28502770; DOI: 10.1016/j.cell.2017.04.033

Experimental method

ELECTRON MICROSCOPY (3.6 Å)