2KWU
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![BU of 2kwu by Molmil](/molmil-images/mine/2kwu) | Solution Structure of UBM2 of murine Polymerase iota in Complex with Ubiquitin | 分子名称: | DNA polymerase iota, Ubiquitin | 著者 | Burschowsky, D, Rudolf, F, Rabut, G, Herrmann, T, Peter, M, Wider, G. | 登録日 | 2010-04-19 | 公開日 | 2010-10-06 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural analysis of the conserved ubiquitin-binding motifs (UBMs) of the translesion polymerase iota in complex with ubiquitin. J.Biol.Chem., 286, 2011
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2KWV
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![BU of 2kwv by Molmil](/molmil-images/mine/2kwv) | Solution Structure of UBM1 of murine Polymerase iota in Complex with Ubiquitin | 分子名称: | DNA polymerase iota, Ubiquitin | 著者 | Burschowsky, D, Rudolf, F, Rabut, G, Herrmann, T, Peter, M, Wider, G. | 登録日 | 2010-04-20 | 公開日 | 2010-10-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural analysis of the conserved ubiquitin-binding motifs (UBMs) of the translesion polymerase iota in complex with ubiquitin. J.Biol.Chem., 286, 2011
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2HD5
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![BU of 2hd5 by Molmil](/molmil-images/mine/2hd5) | USP2 in complex with ubiquitin | 分子名称: | Polyubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ZINC ION | 著者 | Renatus, M, Kroemer, M. | 登録日 | 2006-06-20 | 公開日 | 2006-08-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Basis of Ubiquitin Recognition by the Deubiquitinating Protease USP2. Structure, 14, 2006
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2L00
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![BU of 2l00 by Molmil](/molmil-images/mine/2l00) | Solution structure of the non-covalent complex of the ZNF216 A20 domain with ubiquitin | 分子名称: | Ubiquitin, ZINC ION, Zfand5 protein (Zinc finger protein 216 (Predicted), ... | 著者 | Garner, T.P, Long, J.E, Searle, M.S, Layfield, R. | 登録日 | 2010-06-29 | 公開日 | 2011-07-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Co-localisation of ubiquitin receptors ZNF216 and p62 in a ubiquitin-mediated ternary complex To be Published
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2L0F
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![BU of 2l0f by Molmil](/molmil-images/mine/2l0f) | |
2NBW
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![BU of 2nbw by Molmil](/molmil-images/mine/2nbw) | |
2HTH
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![BU of 2hth by Molmil](/molmil-images/mine/2hth) | Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain | 分子名称: | Ubiquitin, Vacuolar protein sorting protein 36 | 著者 | Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I. | 登録日 | 2006-07-25 | 公開日 | 2006-10-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat.Struct.Mol.Biol., 13, 2006
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2MRO
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![BU of 2mro by Molmil](/molmil-images/mine/2mro) | |
2MUR
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![BU of 2mur by Molmil](/molmil-images/mine/2mur) | |
2JY6
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![BU of 2jy6 by Molmil](/molmil-images/mine/2jy6) | |
2NBV
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![BU of 2nbv by Molmil](/molmil-images/mine/2nbv) | |
2L0T
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![BU of 2l0t by Molmil](/molmil-images/mine/2l0t) | Solution structure of the complex of ubiquitin and the VHS domain of Stam2 | 分子名称: | Signal transducing adapter molecule 2, Ubiquitin | 著者 | Lange, A, Hoeller, D, Wienk, H, Marcillat, O, Lancelin, J, Walker, O. | 登録日 | 2010-07-15 | 公開日 | 2010-12-15 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR reveals a different mode of binding of the Stam2 VHS domain to ubiquitin and diubiquitin. Biochemistry, 50, 2011
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2QHO
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8BS9
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![BU of 8bs9 by Molmil](/molmil-images/mine/8bs9) | |
8BS3
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![BU of 8bs3 by Molmil](/molmil-images/mine/8bs3) | Structure of USP36 in complex with Fubi-PA | 分子名称: | 40S ribosomal protein S30, Ubiquitin carboxyl-terminal hydrolase 36, ZINC ION, ... | 著者 | O'Dea, R, Gersch, M. | 登録日 | 2022-11-24 | 公開日 | 2023-07-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular basis for ubiquitin/Fubi cross-reactivity in USP16 and USP36. Nat.Chem.Biol., 19, 2023
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8C13
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![BU of 8c13 by Molmil](/molmil-images/mine/8c13) | Crystal structure of pVHL:ElonginC:ElonginB complex bound to PROTAC JW48 | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[3-[2-[2-[2-(acetamidomethyl)-4-(6,7-dihydro-5~{H}-pyrrolo[1,2-a]imidazol-2-yl)phenoxy]ethoxy]ethoxy]propanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Kraemer, A, Weckesser, J, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-12-20 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization. Cell Chem Biol, 30, 2023
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8C07
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8CX9
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![BU of 8cx9 by Molmil](/molmil-images/mine/8cx9) | Structure of the SARS-COV2 PLpro (C111S) in complex with a dimeric Ubv that inhibits activity by an unusual allosteric mechanism | 分子名称: | BROMIDE ION, CHLORIDE ION, Papain-like protease nsp3, ... | 著者 | Singer, A.U, Slater, C.L, Patel, A, Russel, R, Mark, B.L, Sidhu, S.S. | 登録日 | 2022-05-20 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site. Plos Pathog., 18, 2022
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8CX2
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![BU of 8cx2 by Molmil](/molmil-images/mine/8cx2) | Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 2 | 分子名称: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | 著者 | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | 登録日 | 2022-05-19 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature, 615, 2023
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8CX0
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![BU of 8cx0 by Molmil](/molmil-images/mine/8cx0) | Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC monomeric complex | 分子名称: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | 著者 | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | 登録日 | 2022-05-19 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature, 615, 2023
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8CX1
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![BU of 8cx1 by Molmil](/molmil-images/mine/8cx1) | Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 1 | 分子名称: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | 著者 | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | 登録日 | 2022-05-19 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature, 615, 2023
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8B7F
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8CQL
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![BU of 8cql by Molmil](/molmil-images/mine/8cql) | pVHL:EloB:EloC in complex with (2S,4R)-N-((S)-1-(5-Fluoro-2-methoxy-4-(4-methylthiazol-5-yl)phenyl)ethyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide (Compound 33) | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-~{N}-[(1~{S})-1-[5-fluoranyl-2-methoxy-4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Casement, R, Phuong Vu, L, Ciulli, A, Gutschow, M. | 登録日 | 2023-03-06 | 公開日 | 2023-09-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1 alpha Stabilizers. J.Med.Chem., 66, 2023
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8CAF
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![BU of 8caf by Molmil](/molmil-images/mine/8caf) | N8C_Fab3b in complex with NEDD8-CUL1(WHB) | 分子名称: | Cullin-1, Fab Heavy Chain, Fab Light Chain, ... | 著者 | Duda, D.M, Yanishevski, D, Henneberg, L.T, Schulman, B.A. | 登録日 | 2023-01-24 | 公開日 | 2023-09-13 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Activity-based profiling of cullin-RING E3 networks by conformation-specific probes. Nat.Chem.Biol., 19, 2023
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8CQK
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![BU of 8cqk by Molmil](/molmil-images/mine/8cqk) | pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-(1-Fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(2-methyl-4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide (Compound 30) | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-~{N}-[(1~{S})-1-[2-methyl-4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Casement, R, Phuong Vu, L, Ciulli, A, Gutschow, M. | 登録日 | 2023-03-06 | 公開日 | 2023-09-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1 alpha Stabilizers. J.Med.Chem., 66, 2023
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